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1دورية أكاديمية
المؤلفون: Gastaldi, Giacomo Gianni Giuseppe, Rocha Gomes, Diana Bianca, Schneiter, Philippe, Montet, Xavier Cédric Rodolphe, Tappy, Luc, Clement, Sophie, Negro, Francesco
المصدر: ISSN: 1932-6203 ; PLOS ONE, vol. 14, no. 6 (2019) e0217751.
مصطلحات موضوعية: info:eu-repo/classification/ddc/616, info:eu-repo/classification/ddc/616.07, info:eu-repo/classification/ddc/616.0757, Adenine Nucleotides/pharmacology, Animals, Biological Transport/drug effects, Cyclic AMP/metabolism, Cyclooxygenase Inhibitors, Lymphocyte Activation, Lymphocytes/immunology/metabolism, Phytohemagglutinins/pharmacology, Prostaglandins E/metabolism, Swine, Uridine/metabolism
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31170218; https://archive-ouverte.unige.ch/unige:123540Test; unige:123540
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2دورية أكاديمية
المؤلفون: Tabrizi, Sarah J, Leavitt, Blair R, Rosser, Anne, Kordasiewicz, Holly B, Czech, Christian, Swayze, Eric E, Norris, Daniel A, Baumann, Tiffany, Gerlach, Irene, Schobel, Scott A, Paz, Erika, Smith, Anne V, Landwehrmeyer, G Bernhard, Bennett, C Frank, Lane, Roger M, Teams, Phase 1–2a IONIS-HTTRx Study Site, McColgan, Peter, Hensman, Davina, Ghosh, Rhia, Flower, Michael, Libri, Vincenzo, Saunders, Edwina, Raymond, Lynn, Wild, Edward J, Decolongon, Joji, Li, Tuan, Fathinia, Panteha, Lang, Christina, Lewerenz, Jan, Lindenberg, Katrin, Ludolph, Albert C, Schneider, Ariane, Trautmann, Sonja, Uhl, Stefanie, Saft, Carsten, Weydt, Patrick, Kaminski, Barbara, Kaminski, Daniela, Hoffmann, Rainer, von Hein, Sarah M, Muhlack, Siegfried, Gold, Ralf, Collins, Lucy, Mason, Sarah, Scott, Kirsten, Barker, Roger A, Stoker, Tom, Greenland, Julia, Andresen, Katie, Shanmugam, Mohan, Abdelghani, Mowafak, Turgut, Tolga, Peeren, Siofra, Colaco, Olga, Owens, Rebecca, Subin, Sujamole, Blair, Nick F, Spruth, Eike Jakob, Beckmann, Janna, Krug, Henriette, Langenfurth, Anika, Crossley, Diana, Akhtar, Nasreen, Gavin, Jennie, De Souza, Jenny, Massey, Thomas, McLauchlan, Duncan, Craufurd, David, Cousins, Rebecca, Shastin, Dmitri, Peall, Kathryn, Bhatt, Harsh, Davison, Andrew, Bagshawe, Joanne, Gunning, Belinda, Hamandi, Khalid, Priller, Josef, Rickards, Hugh
المصدر: The New England journal of medicine 380(24), 2307-2316 (2019). doi:10.1056/NEJMoa1900907
مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Adult, Dose-Response Relationship, Drug, Female, Humans, Huntingtin Protein: antagonists & inhibitors, Huntingtin Protein: cerebrospinal fluid, Huntingtin Protein: genetics, Huntington Disease: drug therapy, Injections, Spinal, Male, Middle Aged, Mutation, Nucleotides: chemical synthesis, Nucleotides: pharmacology, Oligonucleotides: cerebrospinal fluid, Oligonucleotides: therapeutic use, HTT protein, human, HTT(RX), Huntingtin Protein, Nucleotides, Oligonucleotides
جغرافية الموضوع: DE
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/pmid:31059641; info:eu-repo/semantics/altIdentifier/issn/0028-4793; info:eu-repo/semantics/altIdentifier/issn/1533-4406; https://pub.dzne.de/record/140752Test; https://pub.dzne.de/search?p=id:%22DZNE-2020-07074%22Test
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3دورية أكاديمية
المؤلفون: Kuhlmann, F.M., Robinson, J.I., Bluemling, G.R., Ronet, C., Fasel, N., Beverley, S.M.
المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 5, pp. E811-E819
مصطلحات موضوعية: Animals, Antiviral Agents/pharmacology, Capsid Proteins/genetics, Capsid Proteins/metabolism, Leishmania braziliensis/virology, Leishmania guyanensis/virology, Leishmaniasis/parasitology, Leishmaniavirus/drug effects, Leishmaniavirus/genetics, Leishmaniavirus/metabolism, Mice, Inbred C57BL, Nucleosides/pharmacology, Nucleotides/pharmacology, chemotherapy, endobiont virus, trypanosomatid protozoan parasite, viral segregation, virulence
وصف الملف: application/pdf
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28096399; info:eu-repo/semantics/altIdentifier/eissn/1091-6490; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_9466129FAB720; https://serval.unil.ch/notice/serval:BIB_9466129FAB72Test; urn:issn:0027-8424; https://serval.unil.ch/resource/serval:BIB_9466129FAB72.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9466129FAB720Test
الإتاحة: https://doi.org/10.1073/pnas.1619114114Test
https://serval.unil.ch/notice/serval:BIB_9466129FAB72Test
https://serval.unil.ch/resource/serval:BIB_9466129FAB72.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9466129FAB720Test -
4دورية أكاديمية
المؤلفون: Amiable, Claire, Paoletti, Julie, Haouz, Ahmed, Padilla, André, Labesse, Gilles, Kaminski, Pierre-Alexandre, Pochet, Sylvie
المساهمون: Université Paris Descartes - Paris 5 (UPD5), Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Cristallographie (Plateforme) - Crystallography (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by grants from the Fondation pour la Recherche Médicale (DCM20111223063 to S. Pochet), Institut Pasteur, CNRS, INSERM and the French Infrastructure for Integrated Structural Biology (FRISBI, ANR-10-INSB-05-01)., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)
المصدر: ISSN: 0223-5234.
مصطلحات موضوعية: Cancer, Cross-coupling reaction, Crystal structure, DNPH1, Inhibitor, Nucleoside analogues, MESH: Animals, MESH: Antineoplastic Agents/chemical synthesis, MESH: Enzyme Inhibitors/chemistry, MESH: Enzyme Inhibitors/metabolism, MESH: Enzyme Inhibitors/pharmacology, MESH: Humans, MESH: Molecular Docking Simulation, MESH: Molecular Targeted Therapy, MESH: N-Glycosyl Hydrolases/antagonists & inhibitors, MESH: N-Glycosyl Hydrolases/chemistry, MESH: N-Glycosyl Hydrolases/metabolism, MESH: Nuclear Proteins/antagonists & inhibitors, MESH: Antineoplastic Agents/chemistry, MESH: Nuclear Proteins/chemistry, MESH: Nuclear Proteins/metabolism, MESH: Protein Conformation, MESH: Proto-Oncogene Proteins/antagonists & inhibitors, MESH: Proto-Oncogene Proteins/chemistry, MESH: Proto-Oncogene Proteins/metabolism, MESH: Purine Nucleotides/chemical synthesis, MESH: Purine Nucleotides/chemistry, MESH: Purine Nucleotides/metabolism, MESH: Purine Nucleotides/pharmacology, MESH: Antineoplastic Agents/metabolism
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25108359; pasteur-01483767; https://pasteur.hal.science/pasteur-01483767Test; PUBMED: 25108359
الإتاحة: https://doi.org/10.1016/j.ejmech.2014.07.110Test
https://pasteur.hal.science/pasteur-01483767Test -
5دورية أكاديمية
المؤلفون: Amiable, Claire, Paoletti, Julie, Haouz, Ahmed, Padilla, André, Labesse, Gilles, Kaminski, Pierre-Alexandre, Pochet, Sylvie
المساهمون: Université Paris Descartes - Paris 5 (UPD5), Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Cristallographie (Plateforme) - Crystallography (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by grants from the Fondation pour la Recherche Médicale (DCM20111223063 to S. Pochet), Institut Pasteur, CNRS, INSERM and the French Infrastructure for Integrated Structural Biology (FRISBI, ANR-10-INSB-05-01)., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)
المصدر: ISSN: 0223-5234.
مصطلحات موضوعية: Cancer, Cross-coupling reaction, Crystal structure, DNPH1, Inhibitor, Nucleoside analogues, MESH: Animals, MESH: Antineoplastic Agents/chemical synthesis, MESH: Enzyme Inhibitors/chemistry, MESH: Enzyme Inhibitors/metabolism, MESH: Enzyme Inhibitors/pharmacology, MESH: Humans, MESH: Molecular Docking Simulation, MESH: Molecular Targeted Therapy, MESH: N-Glycosyl Hydrolases/antagonists & inhibitors, MESH: N-Glycosyl Hydrolases/chemistry, MESH: N-Glycosyl Hydrolases/metabolism, MESH: Nuclear Proteins/antagonists & inhibitors, MESH: Antineoplastic Agents/chemistry, MESH: Nuclear Proteins/chemistry, MESH: Nuclear Proteins/metabolism, MESH: Protein Conformation, MESH: Proto-Oncogene Proteins/antagonists & inhibitors, MESH: Proto-Oncogene Proteins/chemistry, MESH: Proto-Oncogene Proteins/metabolism, MESH: Purine Nucleotides/chemical synthesis, MESH: Purine Nucleotides/chemistry, MESH: Purine Nucleotides/metabolism, MESH: Purine Nucleotides/pharmacology, MESH: Antineoplastic Agents/metabolism
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25108359; pasteur-01483767; https://pasteur.hal.science/pasteur-01483767Test; PUBMED: 25108359
الإتاحة: https://doi.org/10.1016/j.ejmech.2014.07.110Test
https://pasteur.hal.science/pasteur-01483767Test -
6دورية أكاديمية
المؤلفون: Amiable, Claire, Paoletti, Julie, Haouz, Ahmed, Padilla, André, Labesse, Gilles, Kaminski, Pierre-Alexandre, Pochet, Sylvie
المساهمون: Université Paris Descartes - Paris 5 (UPD5), Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Cristallographie (Plateforme) - Crystallography (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by grants from the Fondation pour la Recherche Médicale (DCM20111223063 to S. Pochet), Institut Pasteur, CNRS, INSERM and the French Infrastructure for Integrated Structural Biology (FRISBI, ANR-10-INSB-05-01)., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)
المصدر: ISSN: 0223-5234.
مصطلحات موضوعية: Cancer, Cross-coupling reaction, Crystal structure, DNPH1, Inhibitor, Nucleoside analogues, MESH: Animals, MESH: Antineoplastic Agents/chemical synthesis, MESH: Enzyme Inhibitors/chemistry, MESH: Enzyme Inhibitors/metabolism, MESH: Enzyme Inhibitors/pharmacology, MESH: Humans, MESH: Molecular Docking Simulation, MESH: Molecular Targeted Therapy, MESH: N-Glycosyl Hydrolases/antagonists & inhibitors, MESH: N-Glycosyl Hydrolases/chemistry, MESH: N-Glycosyl Hydrolases/metabolism, MESH: Nuclear Proteins/antagonists & inhibitors, MESH: Antineoplastic Agents/chemistry, MESH: Nuclear Proteins/chemistry, MESH: Nuclear Proteins/metabolism, MESH: Protein Conformation, MESH: Proto-Oncogene Proteins/antagonists & inhibitors, MESH: Proto-Oncogene Proteins/chemistry, MESH: Proto-Oncogene Proteins/metabolism, MESH: Purine Nucleotides/chemical synthesis, MESH: Purine Nucleotides/chemistry, MESH: Purine Nucleotides/metabolism, MESH: Purine Nucleotides/pharmacology, MESH: Antineoplastic Agents/metabolism
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25108359; pasteur-01483767; https://pasteur.hal.science/pasteur-01483767Test; PUBMED: 25108359
الإتاحة: https://doi.org/10.1016/j.ejmech.2014.07.110Test
https://pasteur.hal.science/pasteur-01483767Test -
7دورية أكاديمية
المؤلفون: Amiable, Claire, Paoletti, Julie, Haouz, Ahmed, Padilla, André, Labesse, Gilles, Kaminski, Pierre-Alexandre, Pochet, Sylvie
المساهمون: Université Paris Descartes - Paris 5 (UPD5), Chimie et Biocatalyse, Institut Pasteur Paris -Centre National de la Recherche Scientifique (CNRS), Cristallographie (Plateforme) - Crystallography (Platform), Centre de Biochimie Structurale Montpellier (CBS), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by grants from the Fondation pour la Recherche Médicale (DCM20111223063 to S. Pochet), Institut Pasteur, CNRS, INSERM and the French Infrastructure for Integrated Structural Biology (FRISBI, ANR-10-INSB-05-01)., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)
المصدر: ISSN: 0223-5234.
مصطلحات موضوعية: Cancer, Cross-coupling reaction, Crystal structure, DNPH1, Inhibitor, Nucleoside analogues, MESH: Animals, MESH: Antineoplastic Agents/chemical synthesis, MESH: Enzyme Inhibitors/chemistry, MESH: Enzyme Inhibitors/metabolism, MESH: Enzyme Inhibitors/pharmacology, MESH: Humans, MESH: Molecular Docking Simulation, MESH: Molecular Targeted Therapy, MESH: N-Glycosyl Hydrolases/antagonists & inhibitors, MESH: N-Glycosyl Hydrolases/chemistry, MESH: N-Glycosyl Hydrolases/metabolism, MESH: Nuclear Proteins/antagonists & inhibitors, MESH: Antineoplastic Agents/chemistry, MESH: Nuclear Proteins/chemistry, MESH: Nuclear Proteins/metabolism, MESH: Protein Conformation, MESH: Proto-Oncogene Proteins/antagonists & inhibitors, MESH: Proto-Oncogene Proteins/chemistry, MESH: Proto-Oncogene Proteins/metabolism, MESH: Purine Nucleotides/chemical synthesis, MESH: Purine Nucleotides/chemistry, MESH: Purine Nucleotides/metabolism, MESH: Purine Nucleotides/pharmacology, MESH: Antineoplastic Agents/metabolism
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25108359; pasteur-01483767; https://hal-pasteur.archives-ouvertes.fr/pasteur-01483767Test; PUBMED: 25108359
الإتاحة: https://doi.org/10.1016/j.ejmech.2014.07.110Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01483767Test -
8دورية أكاديمية
المؤلفون: Amiable, Claire, Paoletti, Julie, Haouz, Ahmed, Padilla, André, Labesse, Gilles, Kaminski, Pierre-Alexandre, Pochet, Sylvie
المساهمون: Université Paris Descartes - Paris 5 (UPD5), Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Cristallographie (Plateforme) - Crystallography (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by grants from the Fondation pour la Recherche Médicale (DCM20111223063 to S. Pochet), Institut Pasteur, CNRS, INSERM and the French Infrastructure for Integrated Structural Biology (FRISBI, ANR-10-INSB-05-01)., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)
المصدر: ISSN: 0223-5234.
مصطلحات موضوعية: Cancer, Cross-coupling reaction, Crystal structure, DNPH1, Inhibitor, Nucleoside analogues, MESH: Animals, MESH: Antineoplastic Agents/chemical synthesis, MESH: Enzyme Inhibitors/chemistry, MESH: Enzyme Inhibitors/metabolism, MESH: Enzyme Inhibitors/pharmacology, MESH: Humans, MESH: Molecular Docking Simulation, MESH: Molecular Targeted Therapy, MESH: N-Glycosyl Hydrolases/antagonists & inhibitors, MESH: N-Glycosyl Hydrolases/chemistry, MESH: N-Glycosyl Hydrolases/metabolism, MESH: Nuclear Proteins/antagonists & inhibitors, MESH: Antineoplastic Agents/chemistry, MESH: Nuclear Proteins/chemistry, MESH: Nuclear Proteins/metabolism, MESH: Protein Conformation, MESH: Proto-Oncogene Proteins/antagonists & inhibitors, MESH: Proto-Oncogene Proteins/chemistry, MESH: Proto-Oncogene Proteins/metabolism, MESH: Purine Nucleotides/chemical synthesis, MESH: Purine Nucleotides/chemistry, MESH: Purine Nucleotides/metabolism, MESH: Purine Nucleotides/pharmacology, MESH: Antineoplastic Agents/metabolism
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25108359; pasteur-01483767; https://pasteur.hal.science/pasteur-01483767Test; PUBMED: 25108359
الإتاحة: https://doi.org/10.1016/j.ejmech.2014.07.110Test
https://pasteur.hal.science/pasteur-01483767Test -
9دورية أكاديمية
مصطلحات موضوعية: Adenine Nucleotides - Pharmacology, Animals, Binding, Competitive, Blood Glucose - Metabolism, Deoxyglucose - Pharmacology, Guanine Nucleotides - Pharmacology, Hepatocytes - Drug Effects - Metabolism, Hyperglycemia - Metabolism, Hypoglycemia - Metabolism, Insulin - Pharmacology, Kinetics, Melatonin - Analogs & Derivatives - Metabolism - Pharmacology, Mice, Receptors, Cell Surface - Classification - Drug Effects - Metabolism, Cytoplasmic And Nuclear - Classification - Drug Effects - Metabolism, Melatonin
العلاقة: Biological Signals and Receptors; http://www.scopus.com/mlt/select.url?eid=2-s2.0-0035200294&selection=ref&src=s&origin=recordpageTest; Biological Signals And Receptors, 2001, v. 10 n. 6, p. 367-379; 379; WOS:000172784600003; eid_2-s2.0-0035200294; 367; http://hdl.handle.net/10722/171696Test; 10
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10دورية أكاديمية
المؤلفون: Bar, Isabelle, Guns, Pieter-Jan D F, Metallo, Jessica, Cammarata, Dorothée, Wilkin, Françoise, Boeynaems, Jean-Marie, Bult, Hidde, Robaye, Bernard
المصدر: Molecular pharmacology, 74 (3
مصطلحات موضوعية: Sciences bio-médicales et agricoles, Animals, Aorta -- drug effects, Aorta -- metabolism, Cytokines -- biosynthesis, Endothelial Cells -- drug effects, Endothelial Cells -- metabolism, Extracellular Signal-Regulated MAP Kinases -- metabolism, Gene Deletion, Gene Expression Regulation -- drug effects, Inositol Phosphates -- biosynthesis, Lipopolysaccharides -- pharmacology, MAP Kinase Signaling System -- drug effects, Macrophages, Peritoneal -- drug effects, Peritoneal -- enzymology, Peritoneal -- metabolism, Mice, Knockout, Muscle Contraction -- drug effects, Muscle Relaxation -- drug effects, Muscle, Smooth, Vascular -- cytology, Myocytes, Smooth Muscle -- drug effects, Smooth Muscle -- metabolism, Nucleotides -- pharmacology, Phenylephrine -- pharmacology, RNA
وصف الملف: No full-text files
العلاقة: uri/info:doi/10.1124/mol.108.046904; uri/info:pii/mol.108.046904; uri/info:pmid/18523137; uri/info:scp/50449096581; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50313Test