المؤلفون: Lan, Qiang, Trela, Ewelina, Lindström, Riikka, Satta, Jyoti P., Kaczynska, Beata, Christensen, Mona M., Holzenberger, Martin, Jernvall, Jukka, Mikkola, Marja

المساهمون: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, Medicum, Department of Geosciences and Geography

مصطلحات موضوعية: IGF-1, Mouse, Wnt, Branching morphogenesis, Ectodysplasin A, Epithelial-mesenchymal interaction, Mammary gland, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: Lan , Q , Trela , E , Lindström , R , Satta , J P , Kaczynska , B , Christensen , M M , Holzenberger , M , Jernvall , J & Mikkola , M 2024 , ' Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland ' , eLife , vol. 13 , e93326 . https://doi.org/10.7554/eLife.93326Test; ORCID: /0000-0002-2530-1841/work/158612645; ORCID: /0000-0002-7765-6767/work/158619297; http://hdl.handle.net/10138/574812Test; 460037b7-1aac-400d-b3ec-063a78205873; 001189583400001

الإتاحة: http://hdl.handle.net/10138/574812Test

المؤلفون: Sulic, Ana-Marija, Roy, Rishi Das, Papagno, Verdiana, Lan, Qiang, Saikkonen, Riikka, Jernvall, Jukka, Thesleff, Irma, Mikkola, Marja L.

المساهمون: Institute of Biotechnology, CAN-PRO - Translational Cancer Medicine Program, Department of Geosciences and Geography, Jukka Jernvall / Principal Investigator, Marja Mikkola / Principal Investigator

مصطلحات موضوعية: Gene-expression, Sonic-hedgehog, Skin appendage, Kappa-b, Enrichment analysis, Unexpected role, Cell-migration, Stem-cells, Differentiation, Ectodysplasin, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: Sulic , A-M , Roy , R D , Papagno , V , Lan , Q , Saikkonen , R , Jernvall , J , Thesleff , I & Mikkola , M L 2023 , ' Transcriptomic landscape of early hair follicle and epidermal development ' , Cell Reports , vol. 42 , no. 6 , 112643 . https://doi.org/10.1016/j.celrep.2023.112643Test; ORCID: /0000-0002-3276-7279/work/139506596; ORCID: /0000-0002-6915-9146/work/155091548; ORCID: /0000-0002-7765-6767/work/155659587; http://hdl.handle.net/10138/563492Test; 535efd64-6283-4d4e-ba7b-b649523270a0; 001022609100001

الإتاحة: http://hdl.handle.net/10138/563492Test

المؤلفون: Zimm, Roland, Oberdick, Danielle, Gnetneva, Anna, Schneider, Pascal, Cebra-Thomas, Judith, Moustakas-Verho, Jacqueline E.

المساهمون: Organismal and Evolutionary Biology Research Programme, Biosciences, Genetics, Evolution, Conservation, and Genomics

مصطلحات موضوعية: ectodermal appendage, evo devo, mathematical model, pattern formation, turtle shell, PATTERN-FORMATION, ANTI-ECTODYSPLASIN, EVO-DEVO, INDUCTION, RECEPTOR, MORPHOGENESIS, EXPRESSION, EVOLUTION, BMPS, FOLLISTATIN, 1181 Ecology, evolutionary biology

وصف الملف: application/pdf

العلاقة: This project was funded by grants from the Academy of Finland (grant numbers 324369 and 309449 to J. M. V.) and the National Science Foundation (award NSF 1457177 to J. C. T.). P. S. is funded by the Swiss National Science Foundation (grant 310030_205196). The authors thank Marko Hyvonen for Activin A protein and Marja Mikkola for facilitating the transfer of anti-EDA antibodies and Activin A protein. The authors also thank two anonymous reviewers whose constructive comments have contributed to improving this research paper.; Zimm , R , Oberdick , D , Gnetneva , A , Schneider , P , Cebra-Thomas , J & Moustakas-Verho , J E 2023 , ' Turing's turtles all the way down : A conserved role of EDAR in the carapacial ridge suggests a deep homology of prepatterns across ectodermal appendages ' , Anatomical Record , vol. 306 , no. 6 , pp. 1201-1213 . https://doi.org/10.1002/ar.25096Test; ORCID: /0000-0001-9702-0945/work/138277482; a74cd6b6-2a28-4037-8387-6be586d10a72; http://hdl.handle.net/10138/563068Test; 000867769500001

الإتاحة: http://hdl.handle.net/10138/563068Test

المؤلفون: Holm Schneider, Christine Schweikl, Florian Faschingbauer, Smail Hadj-Rabia, Pascal Schneider

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7155

مصطلحات موضوعية: ectodermal dysplasia, ectodysplasin A, AlphaLisa, protein replacement, sweat glands, tooth development, prenatal therapy

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/ijms24087155Test

الإتاحة: https://doi.org/10.3390/ijms24087155Test

المؤلفون: Holm Schneider, Smail Hadj-Rabia, Florian Faschingbauer, Christine Bodemer, Dorothy K. Grange, Mary E. Norton, Riccardo Cavalli, Gianluca Tadini, Holger Stepan, Angus Clarke, Encarna Guillén-Navarro, Sigrun Maier-Wohlfart, Athmane Bouroubi, Florence Porte

المصدر: Genes; Volume 14; Issue 1; Pages: 153

مصطلحات موضوعية: ectodermal dysplasia, sweat glands, anhidrosis, ectodysplasin A, protein replacement, fetal therapy, clinical trial

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/genes14010153Test

الإتاحة: https://doi.org/10.3390/genes14010153Test

المؤلفون: Schneider, H., Schweikl, C., Faschingbauer, F., Hadj-Rabia, S., Schneider, P.

المصدر: International journal of molecular sciences, vol. 24, no. 8, pp. 7155

مصطلحات موضوعية: Child, Pregnancy, Female, Infant, Humans, Male, Preschool, Ectodermal Dysplasia 1, Anhidrotic/genetics, Anhidrotic/therapy, Ectodysplasins/genetics, Ectodermal Dysplasia/genetics, Sweating, Hair, Recombinant Proteins, AlphaLisa, ectodermal dysplasia, ectodysplasin A, prenatal therapy, protein replacement, sweat glands, tooth development

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37108325; info:eu-repo/semantics/altIdentifier/eissn/1422-0067; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_55995EB323AC9; https://serval.unil.ch/notice/serval:BIB_55995EB323ACTest; urn:issn:1422-0067; https://serval.unil.ch/resource/serval:BIB_55995EB323AC.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_55995EB323AC9Test

الإتاحة: https://doi.org/10.3390/ijms24087155Test
https://serval.unil.ch/notice/serval:BIB_55995EB323ACTest
https://serval.unil.ch/resource/serval:BIB_55995EB323AC.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_55995EB323AC9Test

المؤلفون: Sina Reinartz, Christine Weiß, Maike Heppelmann, Marion Hewicker-Trautwein, Maren Hellige, Laure Willen, Karsten Feige, Pascal Schneider, Ottmar Distl

المصدر: Genes, Vol 15, Iss 1, p 8 (2023)

مصطلحات موضوعية: ectodysplasin A, Fleckvieh, missense mutation, collagen triple helix repeat domain, Genetics, QH426-470

العلاقة: https://www.mdpi.com/2073-4425/15/1/8Test; https://doaj.org/toc/2073-4425Test; https://doaj.org/article/7354bf697a594a45aac1f2a5cd033a98Test

الإتاحة: https://doi.org/10.3390/genes15010008Test
https://doaj.org/article/7354bf697a594a45aac1f2a5cd033a98Test

المؤلفون: Holm Schneider, Christine Schweikl, Florian Faschingbauer, Smail Hadj-Rabia, Pascal Schneider

المصدر: International Journal of Molecular Sciences, Vol 24, Iss 8, p 7155 (2023)

مصطلحات موضوعية: ectodermal dysplasia, ectodysplasin A, AlphaLisa, protein replacement, sweat glands, tooth development, Biology (General), QH301-705.5, Chemistry, QD1-999

العلاقة: https://www.mdpi.com/1422-0067/24/8/7155Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test; https://doaj.org/article/7050f1b2245749bab066734303429882Test

الإتاحة: https://doi.org/10.3390/ijms24087155Test
https://doaj.org/article/7050f1b2245749bab066734303429882Test

المؤلفون: WANG Huihui, WU Qing, XU Bin, LING Qi, WU Yiqun

المصدر: 口腔疾病防治, Vol 31, Iss 11, Pp 768-773 (2023)

مصطلحات موضوعية: ectodysplasin a gene, non-syndromic tooth agenesis, syndromic tooth agenesis, hypodontia, oligodontia, whole exome sequencing, sanger sequencing, genomic dna, gene mutation, missense mutation, Medicine

العلاقة: https://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.11.002Test; https://doaj.org/toc/2096-1456Test; https://doaj.org/article/44f82fe1e772488ba51dc79262c575e4Test

الإتاحة: https://doi.org/10.12016/j.issn.2096-1456.2023.11.002Test
https://doaj.org/article/44f82fe1e772488ba51dc79262c575e4Test

المؤلفون: Frontiers Production Office

المصدر: Frontiers in Genetics, Vol 14 (2023)

مصطلحات موضوعية: X-linked hypohidrotic ectodermal dysplasia, Ectodysplasin A, variants of uncertain significance, in silico analysis, functional studies, serum EDA concentration, Genetics, QH426-470

العلاقة: https://www.frontiersin.org/articles/10.3389/fgene.2023.1281631/fullTest; https://doaj.org/toc/1664-8021Test; https://doaj.org/article/860a667b41a34581b0aab505c35ae983Test

الإتاحة: https://doi.org/10.3389/fgene.2023.1281631Test
https://doaj.org/article/860a667b41a34581b0aab505c35ae983Test