دورية أكاديمية
Pushing spatial and temporal resolution for functional and diffusion MRI in the Human Connectome Project
| العنوان: | Pushing spatial and temporal resolution for functional and diffusion MRI in the Human Connectome Project |
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| المؤلفون: | Uğurbil K1, Xu J, Auerbach EJ, Moeller S, Vu AT, Duarte Carvajalino JM, Lenglet C, Wu X, Schmitter S, Van de Moortele PF, Strupp J, Sapiro G, De Martino F, Wang D, Harel N, Garwood M, Chen L, Feinberg DA, Smith SM, Miller KL, Sotiropoulos SN, Jbabdi S, Andersson JL, Behrens TE, Glasser MF, Van Essen DC, Yacoub E, WU Minn HCP Consortium, DE PASQUALE, Francesco |
| المساهمون: | Uğurbil, K1, Xu, J, Auerbach, Ej, Moeller, S, Vu, At, Duarte Carvajalino, Jm, Lenglet, C, Wu, X, Schmitter, S, Van de Moortele, Pf, Strupp, J, Sapiro, G, De Martino, F, Wang, D, Harel, N, Garwood, M, Chen, L, Feinberg, Da, Smith, Sm, Miller, Kl, Sotiropoulos, Sn, Jbabdi, S, Andersson, Jl, Behrens, Te, Glasser, Mf, Van Essen, Dc, Yacoub, E, DE PASQUALE, Francesco, WU Minn HCP, Consortium |
| سنة النشر: | 2013 |
| المجموعة: | IRIS Universita degli Studi di Teramo |
| مصطلحات موضوعية: | Animal, Brain, Connectome, Diffusion Magnetic Resonance Imaging, Human, Image Enhancement, Models, Anatomic, Nerve Net, Spatio-Temporal Analysi, Neurological, Cognitive Neuroscience, Neurology |
| الوصف: | The Human Connectome Project (HCP) relies primarily on three complementary magnetic resonance (MR) methods. These are: 1) resting state functional MR imaging (rfMRI) which uses correlations in the temporal fluctuations in an fMRI time series to deduce '. functional connectivity'; 2) diffusion imaging (dMRI), which provides the input for tractography algorithms used for the reconstruction of the complex axonal fiber architecture; and 3) task based fMRI (tfMRI), which is employed to identify functional parcellation in the human brain in order to assist analyses of data obtained with the first two methods. We describe technical improvements and optimization of these methods as well as instrumental choices that impact speed of acquisition of fMRI and dMRI images at 3. T, leading to whole brain coverage with 2. mm isotropic resolution in 0.7. s for fMRI, and 1.25. mm isotropic resolution dMRI data for tractography analysis with three-fold reduction in total dMRI data acquisition time. Ongoing technical developments and optimization for acquisition of similar data at 7. T magnetic field are also presented, targeting higher spatial resolution, enhanced specificity of functional imaging signals, mitigation of the inhomogeneous radio frequency (RF) fields, and reduced power deposition. Results demonstrate that overall, these approaches represent a significant advance in MR imaging of the human brain to investigate brain function and structure. © 2013 Elsevier Inc. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/23702417; info:eu-repo/semantics/altIdentifier/wos/WOS:000322416000010; volume:80; firstpage:80; lastpage:104; numberofpages:25; journal:NEUROIMAGE; http://hdl.handle.net/11575/95626Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84880328621 |
| DOI: | 10.1016/j.neuroimage.2013.05.012 |
| الإتاحة: | https://doi.org/10.1016/j.neuroimage.2013.05.012Test http://hdl.handle.net/11575/95626Test |
| رقم الانضمام: | edsbas.7D7F029C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.neuroimage.2013.05.012 |
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