دورية أكاديمية
Modulation of host miRNAs by intracellular bacterial pathogens
| العنوان: | Modulation of host miRNAs by intracellular bacterial pathogens |
|---|---|
| المؤلفون: | Kishore Das, Omar Garnica, Subramanian Dhandayuthapani |
| المصدر: | Frontiers in Cellular and Infection Microbiology, Vol 6 (2016) |
| بيانات النشر: | Frontiers Media S.A. |
| سنة النشر: | 2016 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Francisella, Listeria, Macrophages, Mycobacterium, Salmonella, microRNA, Microbiology, QR1-502 |
| الوصف: | MicroRNAs (miRNAs) are short non-coding RNAs that regulate the expression of protein coding genes of viruses and eukaryotes at the post-transcriptional level. The eukaryotic genes regulated by miRNAs include those whose products are critical for biological processes such as cell proliferation, metabolic pathways, immune response, and development. It is now increasingly recognized that modulation of miRNAs associated with biological processes is one of the strategies adopted by bacterial pathogens to survive inside the host cells. In this review, we present an overview of the recent findings on alterations of miRNAs in the host cells by facultative intracellular bacterial pathogens. In addition, we discuss how the altered miRNAs help in the survival of these pathogens in the intracellular environment. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2235-2988 |
| العلاقة: | http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00079/fullTest; https://doaj.org/toc/2235-2988Test; https://doaj.org/article/e3f5c83b15674a91b58833c11c9b971fTest |
| DOI: | 10.3389/fcimb.2016.00079 |
| الإتاحة: | https://doi.org/10.3389/fcimb.2016.00079Test https://doaj.org/article/e3f5c83b15674a91b58833c11c9b971fTest |
| رقم الانضمام: | edsbas.60E77602 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 22352988 |
|---|---|
| DOI: | 10.3389/fcimb.2016.00079 |