المؤلفون: Bond, Diana M., Middleton, Philippa, Levett, Kate M. (S30077), Ham, David P. van der, Crowther, Caroline A., Buchanan, Sarah L., Morris, Jonathan M.

المساهمون: National Institute of Complementary Medicine (Host institution)

مصطلحات موضوعية: XXXXXX - Unknown, pregnancy, childbirth, premature labor

الوصف: Background Current management of preterm prelabour rupture of the membranes (PPROM) involves either initiating birth soon after PPROM or, alternatively, adopting a ’wait and see’ approach (expectant management). It is unclear which strategy is most beneficial for mothers and their babies. This is an update of a Cochrane review published in 2010 (Buchanan 2010). Objectives To assess the effect of planned early birth versus expectant management for women with preterm prelabour rupture of the membranes between 24 and 37 weeks’ gestation for fetal, infant and maternal well being. Search methods We searched Cochrane Pregnancy and Childbirth’s Trials Register (30 September 2016), and reference lists of retrieved studies. Selection criteria Randomised controlled trials comparing planned early birth with expectant management for women with PPROM prior to 37 weeks’ gestation. We excluded quasi-randomised trials. Data collection and analysis Two review authors independently evaluated trials for inclusion into the review and for methodological quality. Two review authors independently extracted data. We checked data for accuracy. We assessed the quality of evidence using the GRADE approach. Main results We included 12 trials in the review (3617 women and 3628 babies). For primary outcomes, we identified no clear differences between early birth and expectant management in neonatal sepsis (risk ratio (RR) 0.93, 95% confidence interval (CI) 0.66 to 1.30, 12 trials, 3628 babies, evidence graded moderate), or proven neonatal infection with positive blood culture (RR 1.24, 95% CI 0.70 to 2.21, seven trials, 2925 babies). However, early birth increased the incidence of respiratory distress syndrome (RDS) (RR 1.26, 95% CI 1.05 to 1.53, 12 trials, 3622 babies, evidence graded high). Early birth was also associated with an increased rate of caesarean section (RR 1.26, 95% CI 1.11 to 1.44, 12 trials, 3620 women, evidence graded high). Assessment of secondary perinatal outcomes showed no clear differences in overall perinatal ...

وصف الملف: print

العلاقة: Cochrane Database of Systematic Reviews--1469-493X Vol. 3 No. CD004735

الإتاحة: https://doi.org/10.1002/14651858.CD004735.pub4Test
http://handle.westernsydney.edu.au:8081/1959.7/uws:39277Test

المؤلفون: PICCIONE, EMILIO

المساهمون: Piccione, E

مصطلحات موضوعية: cytokine, icosanoid, oxytocin, steroid hormone, vasopressin, arachidonic acid metabolism, biosynthesi, childbirth, fatty acid synthesi, fetus membrane, human, labor, nonhuman, placenta, premature labor, review, sheep, Settore MED/40 - GINECOLOGIA E OSTETRICIA

الوصف: [No abstract available]

العلاقة: volume:7; issue:1; firstpage:39; lastpage:44; journal:ITALIAN JOURNAL OF GYNAECOLOGY & OBSTETRICS; http://hdl.handle.net/2108/49945Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0029048012

الإتاحة: http://hdl.handle.net/2108/49945Test