دورية أكاديمية

Early Detection of Physical Activity for People With Type 1 Diabetes Mellitus

التفاصيل البيبلوغرافية
العنوان: Early Detection of Physical Activity for People With Type 1 Diabetes Mellitus
المؤلفون: Dasanayake, Isuru S, Bevier, Wendy C, Castorino, Kristin, Pinsker, Jordan E, Seborg, Dale E, Doyle, Francis J, Dassau, Eyal
المصدر: Journal of Diabetes Science and Technology, vol 9, iss 6
بيانات النشر: eScholarship, University of California
سنة النشر: 2015
المجموعة: University of California: eScholarship
مصطلحات موضوعية: Prevention, Diabetes, Clinical Research, Autoimmune Disease, Cardiovascular, Detection, screening and diagnosis, 4.2 Evaluation of markers and technologies, 4.1 Discovery and preclinical testing of markers and technologies, Metabolic and endocrine, Actigraphy, Adolescent, Adult, Aged, Algorithms, Automation, Biomarkers, Blood Glucose, Blood Glucose Self-Monitoring, Diabetes Mellitus, Type 1, Early Diagnosis, Exercise, Exercise Test, Female, Heart Rate, Humans, Hypoglycemia, Hypoglycemic Agents, Insulin Infusion Systems
الوقت: 1236 - 1245
الوصف: BackgroundEarly detection of exercise in individuals with type 1 diabetes mellitus (T1DM) may allow changes in therapy to prevent hypoglycemia. Currently there is limited experience with automated methods that detect the onset and end of exercise in this population. We sought to develop a novel method to quickly and reliably detect the onset and end of exercise in these individuals before significant changes in blood glucose (BG) occur.MethodsSixteen adults with T1DM were studied as outpatients using a diary, accelerometer, heart rate monitor, and continuous glucose monitor for 2 days. These data were used to develop a principal component analysis based exercise detection method. Subjects also performed 60 and 30 minute exercise sessions at 30% and 50% predicted heart rate reserve (HRR), respectively. The detection method was applied to the exercise sessions to determine how quickly the detection of start and end of exercise occurred relative to change in BG.ResultsMild 30% HRR and moderate 50% HRR exercise onset was identified in 6 ± 3 and 5 ± 2 (mean ± SD) minutes, while completion was detected in 3 ± 8 and 6 ± 5 minutes, respectively. BG change from start of exercise to detection time was 1 ± 6 and -1 ± 3 mg/dL, and, from the end of exercise to detection time was 6 ± 4 and -17 ± 13 mg/dL, respectively, for the 2 exercise sessions. False positive and negative ratios were 4 ± 2% and 21 ± 22%.ConclusionsThe novel method for exercise detection identified the onset and end of exercise in approximately 5 minutes, with an average BG change of only -6 mg/dL.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: unknown
العلاقة: qt25f1p5w7; https://escholarship.org/uc/item/25f1p5w7Test
الإتاحة: https://escholarship.org/uc/item/25f1p5w7Test
حقوق: public
رقم الانضمام: edsbas.CCF508BE
قاعدة البيانات: BASE