دورية أكاديمية
Correlation of macrophage location and plaque stress distribution using USPIO-enhanced MRI in a patient with symptomatic severe carotid stenosis: A new insight into risk stratification
| العنوان: | Correlation of macrophage location and plaque stress distribution using USPIO-enhanced MRI in a patient with symptomatic severe carotid stenosis: A new insight into risk stratification |
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| المؤلفون: | Howarth, Simon, Li, Zhi-Yong, Trivedi, Rikin, U-King-Im, Jean Marie, Graves, Martin, Kirkpatrick, Peter, Gillard, Jonathan |
| المصدر: | British Journal of Neurosurgery |
| بيانات النشر: | Informa Healthcare |
| سنة النشر: | 2007 |
| المجموعة: | Queensland University of Technology: QUT ePrints |
| مصطلحات موضوعية: | Atheroma, Carotid, FEA, MRI, Macrophage, Stress |
| الوصف: | High resolution, USPIO-enhanced MR imaging can be used to identify inflamed atherosclerotic plaque. We report a case of a 79-year-old man with a symptomatic carotid stenosis of 82%. The plaque was retrieved for histology and finite element analysis (FEA) based on the preoperative MR imaging was used to predict maximal Von Mises stress on the plaque. Macrophage location correlated with maximal predicted stresses on the plaque. This supports the hypothesis that macrophages thin the fibrous cap at points of highest stress, leading to an increased risk of plaque rupture and subsequent stroke. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | Howarth, Simon, Li, Zhi-Yong, Trivedi, Rikin, U-King-Im, Jean Marie, Graves, Martin, Kirkpatrick, Peter, & Gillard, Jonathan (2007) Correlation of macrophage location and plaque stress distribution using USPIO-enhanced MRI in a patient with symptomatic severe carotid stenosis: A new insight into risk stratification. British Journal of Neurosurgery, 21(4), pp. 396-398.; https://eprints.qut.edu.au/90365Test/; Institute of Health and Biomedical Innovation; Science & Engineering Faculty |
| الإتاحة: | https://doi.org/10.1080/02688690701400775Test https://eprints.qut.edu.au/90365Test/ |
| حقوق: | Consult author(s) regarding copyright matters ; This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au |
| رقم الانضمام: | edsbas.6EE3776A |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |