التفاصيل البيبلوغرافية
| العنوان: |
Autophagy in major human diseases. |
| المؤلفون: |
Daniel J Klionsky (7953596), Giulia Petroni (11539099), Ravi K Amaravadi (11539102), Eric H Baehrecke (7953488), Andrea Ballabio (5579), Patricia Boya (256640), José Manuel Bravo-San Pedro (3621344), Ken Cadwell (777672), Francesco Cecconi (423958), Augustine MK Choi (11539105), Mary E Choi (11539108), Charleen T Chu (11539111), Patrice Codogno (674440), Maria Isabel Colombo (11539114), Ana Maria Cuervo (7181459), Vojo Deretic (82884), Ivan Dikic (24996), Zvulun Elazar (3713575), Eeva-Liisa Eskelinen (728257), Gian Maria Fimia (431159), David A Gewirtz (11539117), Douglas R Green (7953566), Malene Hansen (10367), Marja Jäättelä (127022), Terje Johansen (25018), Gábor Juhász (752374), Vassiliki Karantza (676962), Claudine Kraft (9444050), Guido Kroemer (82802), Nicholas T Ktistakis (9225149), Sharad Kumar (52650), Carlos Lopez-Otin (11539120), Kay F Macleod (10110734), Frank Madeo (360347), Jennifer Martinez (251828), Alicia Meléndez (525432), Noboru Mizushima (46252), Christian Münz (86294), Josef M Penninger (7953629), Rushika M Perera (11539123), Mauro Piacentini (377487), Fulvio Reggiori (90842), David C Rubinsztein (7953644), Kevin M Ryan (686926), Junichi Sadoshima (106970), Laura Santambrogio (86850), Luca Scorrano (382936), Hans-Uwe Simon (340798), Anna Katharina Simon (11539126), Anne Simonsen (774665), Alexandra Stolz (9572985), Nektarios Tavernarakis (47389), Sharon A Tooze (8114291), Tamotsu Yoshimori (127877), Junying Yuan (728818), Zhenyu Yue (198875), Qing Zhong (550817), Lorenzo Galluzzi (82794), Federico Pietrocola (2864783) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Model organisms, Biochemistry & Proteomics, Imaging, Signalling & Oncogenes, Cell Biology, Chemical Biology & High Throughput, aging, cancer, inflammation, metabolic syndromes, neurodegeneration, Tooze FC001187, Developmental Biology, 06 Biological Sciences, 08 Information and Computing Sciences, 11 Medical and Health Sciences |
| الوصف: |
Autophagy is a core molecular pathway for the preservation of cellular and organismal homeostasis. Pharmacological and genetic interventions impairing autophagy responses promote or aggravate disease in a plethora of experimental models. Consistently, mutations in autophagy-related processes cause severe human pathologies. Here, we review and discuss preclinical data linking autophagy dysfunction to the pathogenesis of major human disorders including cancer as well as cardiovascular, neurodegenerative, metabolic, pulmonary, renal, infectious, musculoskeletal, and ocular disorders. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/journal_contribution/Autophagy_in_major_human_diseases_/16775662Test |
| DOI: |
10.25418/crick.16775662.v1 |
| الإتاحة: |
https://doi.org/10.25418/crick.16775662.v1Test |
| حقوق: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.EBE211FE |
| قاعدة البيانات: |
BASE |
