دورية أكاديمية
Molecular and Biochemical Parameters Related to Plasma Mannose Levels in Coronary Artery Disease among Nondiabetic Patients
| العنوان: | Molecular and Biochemical Parameters Related to Plasma Mannose Levels in Coronary Artery Disease among Nondiabetic Patients |
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| المؤلفون: | Köseler, Aylin, Arslan, I., Sabirli, R., ZeytünlüoÄŸlu, Ali, Klllç, O., Kılıç, Ä°smail DoÄŸu |
| بيانات النشر: | Mary Ann Liebert Inc. |
| سنة النشر: | 2020 |
| المجموعة: | Pamukkale University Repository / Pamukkale Üniversitesi Açık Erişim Arşivi |
| مصطلحات موضوعية: | coronary vascular disease (CAD), insulin, nondiabetic, plasma mannose level, glucose, glucose transporter 1, glucose transporter 4, hexokinase 1, hexokinase 2, mannose, mannose phosphate isomerase, phosphotransferase, unclassified drug, adult, aging, angina pectoris, Article, cardiac patient, cardiovascular risk, controlled study, coronary artery disease, diabetic patient, female, human, gene expression, heart infarction, hyperglycemia, hypertension, incidence, insulin blood level |
| الوصف: | Aims: Nondiabetic patients were studied to determine whether modest elevations in plasma mannose may be associated with a greater incidence of coronary artery disease (CAD). Materials and Methods: Plasma insulin, mannose, glucose, hexokinase 1-2, GLUT1-GLUT4 levels, and serum mannose phosphate isomerase enzyme levels were evaluated with respect to subsequent CAD using records from 120 nondiabetic CAD patients and 120 healthy volunteers. CAD was identified from myocardial infarction and new diagnoses of angina. Results: Of 120 nondiabetic CAD patients studied, their plasma GLUT4 and HK1 levels were significantly lower than those of the control group. In addition, a significant increase in plasma mannose levels was found in the patient group compared to the control group. Conclusion: Our findings showed that elevated baseline mannose levels in plasma are associated with an increased risk of CAD over time. © Copyright 2020, Mary Ann Liebert, Inc., publishers 2020. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1945-0265 |
| العلاقة: | Genetic Testing and Molecular Biomarkers; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11499/37021Test; https://doi.org/10.1089/gtmb.2020.0095Test; 24; 562; 568; 2-s2.0-85090903794; WOS:000558362900001 |
| DOI: | 10.1089/gtmb.2020.0095 |
| الإتاحة: | https://doi.org/10.1089/gtmb.2020.0095Test https://hdl.handle.net/11499/37021Test |
| حقوق: | none |
| رقم الانضمام: | edsbas.494C505D |
| قاعدة البيانات: | BASE |
| تدمد: | 19450265 |
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| DOI: | 10.1089/gtmb.2020.0095 |