دورية أكاديمية
Placental Sampling for Understanding Viral Infections - A Simplified Protocol for the COVID-19 Pandemic
| العنوان: | Placental Sampling for Understanding Viral Infections - A Simplified Protocol for the COVID-19 Pandemic |
|---|---|
| المؤلفون: | Guilherme de Moraes Nobrega, José Paulo Siqueira Guida, Rodolfo Rosa Japecanga, Arthur Antolini-Tavares, Indira Mysorekar, Maria Laura Costa |
| المصدر: | Revista Brasileira de Ginecologia e Obstetrícia, Vol 43, Iss 5, Pp 377-383 (2021) |
| بيانات النشر: | Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
| سنة النشر: | 2021 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | COVID-19, placenta, pregnancy, systematic sampling, viral infections, Gynecology and obstetrics, RG1-991 |
| الوصف: | Objective The coronavirus disease 2019 (COVID-19) is a pandemic viral disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The impact of the disease among the obstetric population remains unclear, and the study of the placenta can provide valuable information. Adequate sampling of the placental tissue can help characterize the pathways of viral infections. Methods A protocol of placental sampling is proposed, aiming at guaranteeing representativity of the placenta and describing the adequate conservation of samples and their integrity for future analysis. The protocol is presented in its complete and simplified versions, allowing its implementation in different complexity settings. Results Sampling with the minimum possible interval from childbirth is the key for adequate sampling and storage. This protocol has already been implemented during the Zika virus outbreak. Conclusion A protocol for adequate sampling and storage of placental tissue is fundamental for adequate evaluation of viral infections on the placenta. During the COVID-19 pandemic, implementation of this protocol may help to elucidate critical aspects of the SARS-CoV-2 infection. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English Portuguese |
| تدمد: | 0100-7203 |
| العلاقة: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021000500377&tlng=enTest; https://doaj.org/toc/0100-7203Test; https://doaj.org/article/f9d41ad2987c45298c6e63ecf90166ddTest |
| DOI: | 10.1055/s-0041-1729146 |
| الإتاحة: | https://doi.org/10.1055/s-0041-1729146Test https://doaj.org/article/f9d41ad2987c45298c6e63ecf90166ddTest |
| رقم الانضمام: | edsbas.DBB375E8 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 01007203 |
|---|---|
| DOI: | 10.1055/s-0041-1729146 |