دورية أكاديمية
Successful Treatment of Intracranial Germ Cell Tumor: Report of Two Unusual Cases and Literature Review
| العنوان: | Successful Treatment of Intracranial Germ Cell Tumor: Report of Two Unusual Cases and Literature Review |
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| المؤلفون: | Ju Hyun Lee, In Sook Woo, Young Yun Cho, Won Jik Lee, Deok Jae Han, Chi Wha Han, Yun Hwa Jung |
| المصدر: | Case Reports in Oncology, Vol 8, Iss 3, Pp 520-525 (2015) |
| بيانات النشر: | Karger Publishers |
| سنة النشر: | 2015 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Intracranial germ cell tumor, Chemotherapy, Radiation therapy, Germinoma, Choriocarcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Primary intracranial germ cell tumor (GCT) is a rare tumor that generally occurs due to developmental anomaly. Although intracranial GCT is sensitive to treatment, a high recurrence rate, treatment-related long-term complications and the heterogeneity of this tumor group make treatment complicated. Moreover, because of its location, hydrocephalus and visual field defect, functional disturbance of the pituitary gland can occur and require attention. Treatment primarily relies on chemotherapy and radiation therapy but the management of intracranial GCT remains unsettled, especially in the case of unusual circumstances such as multifocal tumor or nongerminomatous GCT. Here, we present two unusual cases of intracranial GCT: one case with a bifocal intracranial germinoma, and the other with an intracranial choriocarcinoma. Both cases were treated with neoadjuvant chemotherapy followed by reduced-field radiation therapy without significant treatment-related complication. Further, we performed a PubMed search to investigate the appropriate treatment strategy for this unusual subtype of intracranial GCT. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1662-6575 |
| العلاقة: | http://www.karger.com/Article/FullText/441837Test; https://doaj.org/toc/1662-6575Test; https://doaj.org/article/d36169e381bf4e0aa94543b6345fa40aTest |
| DOI: | 10.1159/000441837 |
| الإتاحة: | https://doi.org/10.1159/000441837Test https://doaj.org/article/d36169e381bf4e0aa94543b6345fa40aTest |
| رقم الانضمام: | edsbas.E2D22D44 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 16626575 |
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| DOI: | 10.1159/000441837 |