التفاصيل البيبلوغرافية
| العنوان: |
Plasmonic probing of the adhesion strength of single microbial cells. |
| المؤلفون: |
Yi-Nan Liu1, Zhen-Ting Lv1, Wen-Li Lv1, Xian-Wei Liu1,2 |
| المصدر: |
Proceedings of the National Academy of Sciences of the United States of America. 11/3/2020, Vol. 117 Issue 44, p1-6. 6p. |
| مصطلحات موضوعية: |
*MICROBIAL cells, *BACTERIAL cells, *ADHESION, *SURFACE interactions, *MICROBIAL adhesion |
| مستخلص: |
Probing the binding between a microbe and surface is critical for understanding biofilm formation processes, developing biosensors, and designing biomaterials, but it remains a challenge. Here, we demonstrate a method to measure the interfacial forces of bacteria attached to the surface. We tracked the intrinsic fluctuations of individual bacterial cells using an interferometric plasmonic imaging technique. Unlike the existing methods, this approach determined the potential energy profile and quantified the adhesion strength of single cells by analyzing the fluctuations. This method provides insights into biofilm formation and can also serve as a promising platform for investigating biological entity/surface interactions, such as pathogenicity, microbial cell capture and detection, and antimicrobial interface screening. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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