دورية أكاديمية

Increased incidence and mortality from Listeria monocytogenes infection in Spain.

التفاصيل البيبلوغرافية
العنوان: Increased incidence and mortality from Listeria monocytogenes infection in Spain.
المؤلفون: Vázquez, Elena1 (AUTHOR), de Gregorio-Vicente, Oscar1 (AUTHOR), Soriano, Vicente1 (AUTHOR), Álvarez-Domínguez, Carmen1 (AUTHOR), Corral, Octavio1 (AUTHOR), Moreno-Torres, Víctor1,2 (AUTHOR) victor.moreno.torres.1988@gmail.com
المصدر: International Journal of Infectious Diseases. Aug2024, Vol. 145, pN.PAG-N.PAG. 1p.
مصطلحات موضوعية: *LISTERIOSIS, *LISTERIA monocytogenes, *COVID-19 pandemic, *STAY-at-home orders, *NEONATAL sepsis, *MORTALITY
مصطلحات جغرافية: SPAIN, ANDALUSIA (Spain)
مستخلص: • The hospitalizations and deaths from listeriosis in Spain have increased since 2000. • This increase was driven by listeriosis in the elderly and immunosuppressed. • An increased incidence in 2019 was related to a large outbreak in Andalusia. • Hospitalizations with Listeria decreased drastically during the COVID-19 pandemic. • Despite being declared a mandatory notifiable disease in 2015, figures are worsening. Listeria monocytogenes (LM) is a health threat worldwide given its high mortality and the growing of high-risk susceptible populations. All hospitalizations with a diagnosis of LM in the National Registry of Hospital Discharges were examined in Spain from 2000 to 2021. A total of 8152 hospital admissions with LM were identified. The mean age was 59.5 years and 48% were immunosuppressed (IS). The rate of LM hospitalizations increased from 5 per 1 million population in 2000 to 8.9 in 2021 (p < 0.001). A foodborne outbreak in Andalusia determined a sharp increase in admissions with LM during 2019. The COVID-19 pandemic and lockdowns were associated with a decrease in LM admissions. The overall in-hospital mortality was 16.7%. The number of deaths in patients hospitalized with LM rose from 7.8 per 100,000 deceased in 2000 to 18 in 2021 (p < 0.001). After adjustment, age >65 years (odds ratio [OR] = 2.16), sepsis (OR = 2.60), meningoencephalitis (OR = 1.72), endocarditis (OR = 2.0), neonatal listeriosis (OR = 2.10) and IS (OR = 2.09) were associated with mortality. The number of patients hospitalized with LM in Spain has increased significantly from 2000 to 2021. The increase in the rate of admissions and deaths was largely driven by the growing proportion of elderly and IS patients. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:12019712
DOI:10.1016/j.ijid.2024.107089