التفاصيل البيبلوغرافية
| العنوان: |
Influence of a 100-km Ultra-Marathon on Hepatitis B Carrier Runners. |
| المؤلفون: |
Y.-H. Chiu1,2, S.-K. Hou2,3, C.-K. How4, L.-H. Li5, W.-F. Kao2,3 wfkao100a@hotmail.com.tw, C.-C. Yang2, S.-L. Chou6, Y.-T. S. Shiau4, C. Lam1, R.-J. Chen1 |
| المصدر: |
International Journal of Sports Medicine. Sep2013, Vol. 34 Issue 9, p841-845. 5p. 4 Charts. |
| مصطلحات موضوعية: |
*ASPARTATE aminotransferase, *C-reactive protein, *CARRIER state (Communicable diseases), *STATISTICAL correlation, *CREATINE kinase, *FISHER exact test, *HEPATITIS B, *INTERLEUKINS, *LACTATE dehydrogenase, *RESEARCH funding, *STATISTICS, *TUMOR necrosis factors, *U-statistics, *DATA analysis, *ALANINE aminotransferase, *LONG-distance running, *CASE-control method, *DATA analysis software, *DESCRIPTIVE statistics |
| مصطلحات جغرافية: |
TAIWAN |
| مستخلص: |
This study compares the serological markers between runners who are hepatitis B virus carries (HBVc) and runners who are non-HBVc in a 100-km ultra-marathon race. Blood samples of 8 HBVc and 18 non-HBVc runners were drawn 1 week before, immediately following, and 24 h after the race. Samples were analyzed and compared between the 2 groups for liver function tests, muscle damage markers and oxidative stress cytokines. For HBVc runners, HBV-DNA (hepatitis B virus-deoxyribonucleic acid) levels were also evaluated for virus reactivation. The results demonstrate a statistically signifi cant increase in both immediate and 24-h post-race values for alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), creatine kinase (CK), high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), compared with pre-race values. No statistically signifi cant diff erence was observed between the 2 groups for the values of AST, LDH, CK, hs-CRP, IL-6 and TNF-α either before or after the race. There was also no statistically signifi cant change in the levels of HBV-DNA in HBVc runners. These findings suggest that HBVc runners do not have higher risks of liver function impairment, muscle breakdown and inflammatory response compared to non-HBVc runners in such endurance races. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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