التفاصيل البيبلوغرافية
| العنوان: |
Predictors of Acute Vertebrobasilar Vasospasm following Tumor Resection in the Foramen Magnum Region. |
| المؤلفون: |
Tao, Chuanyuan1 tcy106@163.com, Wang, Jiajing2, Zhang, Yuekang1, Qi, Shirong1, Liu, Fan2 liufan_ICU@126.com, You, Chao1 |
| المصدر: |
PLoS ONE. 9/28/2016, Vol. 11 Issue 9, p1-9. 9p. |
| مصطلحات موضوعية: |
*BRAIN tumor treatment, *CEREBRAL vasospasm, *SURGICAL excision, *SKULL base, *RETROSPECTIVE studies, *SURGERY, *FORAMEN magnum |
| مستخلص: |
Objective: Cerebral vasospasm can occur after skull base tumor removal. Few studies concentrated on the posterior circulation vasospasm after tumor resection in the posterior fossa. We aimed to identify the risk factors associated with postoperative vertebrobasilar vasospasm after tumor resection in the foramen magnum. Methods: We retrospectively reviewed the data of 62 patients with tumors in the foramen magnum at our institution from January 2010 to January 2015. The demographic data, tumor features, surgical characteristics were collected. Vertebrobasilar vasospasm was evaluated by bedside transcranial Doppler before surgery and on postoperative day 1, 3, 7. Univariate and multivariate analyses were performed to determine the predictors of postoperative vasospasm in the posterior circulation. Results: Vertebrobasilar vasospasm was detected in 28 (53.8%) of the 62 patients at a mean time of 3.5 days after surgery. There were 5 (8%) patients with severe vasospasm according to the grading criteria. Age, tumor type, tumor size, vertebral artery encasement, and surgical time were significantly related to vasospasm in the univariate analysis. Further multivariate analysis demonstrated that only age and vertebral artery encasement were independent risk factors predicting the occurrence of postoperative vertebrobasilar vasospasm. Conclusions: The incidence of acute vertebrobasilar vasospasm is not uncommon after foramen magnum tumor resection. Age and vertebral artery encasement are significantly correlated with postoperative vasospasm. Close monitoring of vasospasm should be given to patients with younger age and the presence of vertebral artery encasement on the preoperative imaging to facilitate early diagnosis and intervention. [ABSTRACT FROM AUTHOR] |
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