التفاصيل البيبلوغرافية
| العنوان: |
"A STUDY ON EVALUATION OF THE UTILITY OF PLEURAL FLUID CHOLESTEROL AND LACTATE DEHYDROGENASE (LDH) IN DIFFERENTIATING EXUDATIVE FROM TRANSUDATIVE PLEURAL EFFUSIONS". |
| المؤلفون: |
H., Sujith1, Udupa, Aniruddha2, Y., Madhu Sudhan1 |
| المصدر: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research). 2022, Vol. 13 Issue 7, p671-681. 11p. |
| مصطلحات موضوعية: |
*PLEURAL effusions, *LACTATE dehydrogenase, *CHOLESTEROL, *DIAPHRAGM walls, *MEDICAL sciences |
| مستخلص: |
Background: Prevalence of Pleural effusion is approximately 400/100000 population. Pleural effusion can manifest as a result of several diseases, both pulmonary and extrapulmonary. The pleura is susceptible to infections due to its direct apposition to other structures. For example, the parietal pleura over the diaphragm and chest wall is resistant to infection, whereas the parietal pleura lying over the mediastinum can be easily invaded by organisms. OBJECTIVES: 1. To determine pleural fluid Cholesterol and LDH from pleural fluid analysis. 2. To determine the cut-off levels for pleural fluid cholesterol and LDH in our set up, given the variability of results from one laboratory to another. MATERIAL & METHODS: Study Design: Prospective hospital based cross - sectional study. Study area: The present study was conducted in the department of TB & Respiratory medicine, Subbaiah Institute of Medical Sciences, Shimoga, Karnataka. Study Period: Mar. 2021 - Feb. 2022. Study population: Patients with Pleural Effusion evaluated in Department of Respiratory Medicine in Subbaiah Institute of Medical Sciences, Shimoga, Karnataka. Statistical analysis: Analysis of variance (ANOVA) has been used to find the significance of study parameters between three or more groups of patients, Student t test (two tailed, independent) has been used to find the significance of study parameters on continuous scale between two groups (Inter group analysis) on metric parameters. Results: Analysing pleural fluid LDH and Cholesterol in exudative pleural effusions using student t test mean LDH level 772.52 + 144.56 was moderately significant and mean cholesterol level 81.36 + 5.30 was strongly significant. Analysing pleural fluid LDH and Cholesterol in transudative pleural effusions using student t test mean LDH level 116.06 + 32.89 was moderately significant and mean cholesterol level 26.25 + 3.64 was strongly significant. CONCLUSION: From our study it can be concluded that, Pleural fluid cholesterol and LDH were found to be excellent pleural fluid parameters for differentiating exudative and transudative effusions from the study. They are both cost effective as well as technically feasible to analyse and hence could serve as better guides in the proper management of pleural effusion. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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