دورية أكاديمية
Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016
العنوان: | Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016 |
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المؤلفون: | Hemminki Kari Jussi, Försti Asta, Hansson Markus |
المصدر: | Scientific Reports 11(1) 10 |
سنة النشر: | 2021 |
المجموعة: | Zenodo |
مصطلحات موضوعية: | Hematopoietic neoplasms, cancer, multiple myeloma, Survival in cancer |
الوصف: | Survival in multiple myeloma (MM) has developed favorably over the past decades for reasons that have been ascribed to new medications and treatment. However, development of survival over a long period and comparison to other hematopoietic neoplasms (HN) is less well known. Here we used Swedish cancer data from the Nordcan database, spanning a 50-year period from 1967 to 2016, and analyzed 1- and 5-year survival data. As a novel type of analysis we calculate the difference in survival between year 1 and 5 which indicates how well survival was maintained in the 4-year period following year 1 after diagnosis. The relative 1- and 5- year survival increased constantly; the 5-year survival graph for women was almost linear. The difference between 1- and 5-year survival revealed that the 5-year survival gain was entirely due to the improvement in 1-year survival, except for the last period. Survival improvement in all HNs exceeded that in MM. The linear 5-year survival increase for female MM patients suggests a contribution by many small improvements in the first year care rather than single major events. The future challenges are to push the gains past year 1 and to extend them to old patients. ; Supported by the European Union's Horizon 2020 research and innovation programme, Grant No. 856620 (Chaperon) and by the German Jose Carreras Leukemia Foundation. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
العلاقة: | info:eu-repo/grantAgreement/EC/H2020/856620/; https://zenodo.org/record/5463712Test; https://doi.org/10.1038/s41598-021-96804-8Test; oai:zenodo.org:5463712 |
DOI: | 10.1038/s41598-021-96804-8 |
الإتاحة: | https://doi.org/10.1038/s41598-021-96804-8Test https://zenodo.org/record/5463712Test |
حقوق: | info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by/4.0/legalcodeTest |
رقم الانضمام: | edsbas.D6B27102 |
قاعدة البيانات: | BASE |
DOI: | 10.1038/s41598-021-96804-8 |
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