التفاصيل البيبلوغرافية
| العنوان: |
Association between depression and subclinical carotid atherosclerosis in patients with Type 1 diabetes |
| المؤلفون: |
Spitzer, C., Völzke, H., Barnow, S., Krohn, U., Wallaschofski, H., Lüdemann, J., John, U., Freyberger, H. J., Kerner, W., Grabe, H. J. |
| المصدر: |
Diabetic Medicine ; volume 25, issue 3, page 349-354 ; ISSN 0742-3071 1464-5491 |
| بيانات النشر: |
Wiley |
| سنة النشر: |
2008 |
| المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: |
Aims Recent studies have suggested an association between depression and subclinical atherosclerosis as measured by presence of carotid atherosclerotic plaque and increased intima‐media thickening in non‐clinical populations. Given the high prevalence of depression in patients with Type 1 diabetes and the diabetes‐related risk factors for atherosclerosis, we hypothesized that this relation might also be of special relevance in Type 1 diabetic patients. Methods Intima‐media thickness (IMT) and the presence of plaques in the carotid arteries were quantitatively assessed by high‐resolution ultrasound in 175 adults (89 men, 86 women) with an established diagnosis of Type 1 diabetes. Having been treated for depression or current Beck Depression Inventory scores > 10 were considered to indicate depression. Results In men, the risk of plaque was higher in depressed subjects relative to non‐depressed participants after adjustment for age, smoking status, systolic blood pressure, dyslipidaemia and body mass index [odds ratio (OR) 5.19; 95% confidence interval (CI) 1.29, 20.81]. Depressed women did not have an increased risk of plaque compared with non‐depressed women (OR 0.97; 95% 95% CI 0.22, 4.34). We did not observe an association between depression and IMT, in men or in women. Conclusions In line with previous research, our findings suggest a link between depression and subclinical atherosclerosis in Type 1 diabetic men, but not in women. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1111/j.1464-5491.2007.02369.x |
| الإتاحة: |
https://doi.org/10.1111/j.1464-5491.2007.02369.xTest |
| حقوق: |
http://onlinelibrary.wiley.com/termsAndConditions#vorTest |
| رقم الانضمام: |
edsbas.6B271C6 |
| قاعدة البيانات: |
BASE |
