التفاصيل البيبلوغرافية
| العنوان: |
Impact of the initial clinical presentation on the outcome of patients with infective endocarditis |
| المؤلفون: |
Motoc, Andreea, Kessels, Jolien, Roosens, Bram, Lacor, Patrick, Van de Veire, Nico, De Sutter, Johan, Magne, Julien, Droogmans, Steven, Cosyns, Bernard |
| المصدر: |
Cardiology Journal; Vol 30, No 3 (2023); 385-390 |
| بيانات النشر: |
Via Medica |
| سنة النشر: |
2023 |
| المجموعة: |
Via Medica Journals |
| مصطلحات موضوعية: |
infective endocarditis, clinical presentation, cardiac surgery, in-hospital mortality |
| الوصف: |
Background: Infective endocarditis (IE) is a life-threatening disease. Despite advancements in diagnosticmethods, the initial clinical presentation of IE remains a valuable asset. Therefore, the impactof clinical presentation on outcomes and its association with microorganisms and IE localization wereassessed herein.Methods: This retrospective study included 183 patients (age 68.9 ± 14.2 years old, 68.9% men)with definite IE at two tertiary care hospitals in Belgium. Demographic data, medical history, clinicalpresentation, blood cultures, imaging data and outcomes were recorded.Results: In-hospital mortality rate was 22.4%. Sixty (32.8%) patients developed embolism, 42 (23%)shock, and 103 (56.3%) underwent surgery during hospitalization. Shock at admission predictedembolism during hospitalization (odds ratio [OR] 2.631, 95% confidence interval [CI] 1.119–6.184,p = 0.027). A new cardiac murmur at admission predicted cardiac surgery (OR 1.949, 95% CI 1.007––3.774, p = 0.048). Methicillin resistant Staphylococcus aureus predicted in-hospital mortality andshock (p = 0.005, OR 6.945, 95% CI 1.774–27.192 and p = 0.015, OR 4.691, 95% CI 1.348–16.322,respectively). Mitral valve and aortic valve IE predicted in-hospital death (p = 0.039, OR 2.258, 95%CI 1.043–4.888) and embolism (p = 0.017, OR 2.328, 95% CI 1.163–4.659), respectively.Conclusions: In this retrospective study, shock at admission independently predicted embolism duringhospitalization in IE patients. Moreover, a new cardiac murmur at admission predicted the needfor cardiac surgery. This emphasizes the importance of a comprehensive initial clinical evaluation incombination with imaging and microbiological data, in order to identify high-risk IE patients early. |
| نوع الوثيقة: |
other/unknown material |
| وصف الملف: |
application/pdf; text/html |
| اللغة: |
English |
| العلاقة: |
https://journals.viamedica.pl/cardiology_journal/article/downloadSuppFile/71547/226037Test; https://journals.viamedica.pl/cardiology_journal/article/view/CJ.a2021.0075Test |
| DOI: |
10.5603/CJ.a2021.0075 |
| الإتاحة: |
https://doi.org/10.5603/CJ.a2021.0075Test
https://journals.viamedica.pl/cardiology_journal/article/view/CJ.a2021.0075Test |
| حقوق: |
Completion of the online submission form electronically is tantamount to automatically and free-of-charge transferring of the copyright for publishing and distribution of the submitted material (in all known now and developed in the future forms and fields of exploitation) to the Publisher, under condition that those materials are accepted for publication. The authors agree not to publish any data or figures presented in their work anywhere and in any language without the prior written consent of the owner of the copyrights, i.e. the Publisher. |
| رقم الانضمام: |
edsbas.5ED8E703 |
| قاعدة البيانات: |
BASE |
