The effectiveness of using dye models for small tissue biopsies in the surgical pathology laboratory

التفاصيل البيبلوغرافية
العنوان: The effectiveness of using dye models for small tissue biopsies in the surgical pathology laboratory
المؤلفون: Nonsiri, Predaporn, Srivilai, Potchara, Onkaew, Supatsorn, Benjakul, Nontawat
المصدر: Folia Histochemica et Cytobiologica; Vol 61, No 2 (2023); 123-129
بيانات النشر: Via Medica
سنة النشر: 2023
المجموعة: Via Medica Journals
مصطلحات موضوعية: tissue biopsy, merbromin, hematoxylin, eosin, crystal violet, alcian blue, tissue marking, Respiratory System, Urogenital System, Digestive System
الوصف: Introduction. Losing of small tissues during tissue preparatory steps may seriously affect pathological diagnostic performance. Using an appropriate tissue marking dye could be an alternative solution. Therefore, the aim of the study was to find a suitable tissue marking dye to enhance the observable ability of various types of small-size tissues during several steps of tissue preparation. Material and methods. Various small-size samples of various organs and tissues (0.2 to 0.3 cm), including breast, endometrial, and cervical tissue, stomach, small and large intestine, lung, and kidney, were marked with different dyes such as merbromin, hematoxylin, eosin, crystal violet, and alcian blue prior to tissue processing step and their colored-observable ability was evaluated by pathology assistants. Moreover, the diagnostic interfering effect of each tissue marking dye was determined by pathologists. Results. Merbromin, hematoxylin, and alcian blue increased the colored-observable ability of small tissue samples. We suggest using hematoxylin as a tissue marking dye over merbromin and alcian blue because of less toxicity and no interference effect in the step of routine pathological slide examination. Conclusions. Hematoxylin could be a suitable tissue marking dye for small-size samples and may improve the preanalytical process of tissue preparation in pathological laboratories.
نوع الوثيقة: other/unknown material
وصف الملف: application/pdf
اللغة: English
العلاقة: https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/FHC.a2023.0008Test
DOI: 10.5603/FHC.a2023.0008
الإتاحة: https://doi.org/10.5603/FHC.a2023.0008Test
https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/FHC.a2023.0008Test
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رقم الانضمام: edsbas.E4831F3A
قاعدة البيانات: BASE