التفاصيل البيبلوغرافية
| العنوان: |
Myocardial infarction with non-obstructive coronary arteries in young women presenting with ST-segment elevation myocardial infarction: a case series |
| المؤلفون: |
Kanji, Rahim, Dinarvand, Danial, Gue, Ying X., Gorog, Diana A. |
| المصدر: |
Medical Research Journal; Vol 5, No 1 (2020); 55-60 |
| بيانات النشر: |
Via Medica |
| سنة النشر: |
2020 |
| المجموعة: |
Via Medica Journals |
| مصطلحات موضوعية: |
MINOCA, STEMI, OCT, thrombus |
| الوصف: |
Introduction. Myocardial infarction with non-obstructive coronary arteries (MINOCA) is an increasingly recognised entity, with comparable mortality to myocardial infarction with obstructive coronary artery disease (CAD).Case presentation. We present the cases of two young females presenting to hospital with ST-segment elevation myocardial infarction without obstructive CAD. Common to both cases was the acute onset of chest pain with no prior cardiac history, minimal cardiac risk factors, and the use of hormone-based contraception. The first patient had an ostially occluded left anterior descending artery (LAD). Flow was restored with balloon inflation and the administration of tirofiban. However, no underlying obstructive CAD was identified, which was confirmed with repeat angiography and optical coherence tomography. The cause was later attributable to plaque erosion, after learning the results of a normal thrombophilia screening. The second patient had ST-segment resolution on arrival to the catheter lab, and on angiography, she had TIMI II flow down the LAD due to significant thrombus burden. Similarly, balloon inflation and tirofiban were administered to improve flow, and non-obstructive CAD was confirmed with repeat angiography and OCT 48 hours later. As with patient 1, this patient too had normal thrombophilia screening results. Both patients were discharged with dual-antiplatelet therapy and secondary prevention, and were advisedagainst hormone-based contraception.Discussion. Patients with MINOCA tend to be younger, with a higher female-to-male preponderance. Multiple causes have been identified, highlighting the importance of following a diagnostic algorithm. This will enable correct treatment, which may differ from that for patients with obstructive coronary disease, thus improving prognosis. |
| نوع الوثيقة: |
other/unknown material |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
https://journals.viamedica.pl/medical_research_journal/article/view/MRJ.a2020.0006Test |
| DOI: |
10.5603/MRJ.a2020.0006 |
| الإتاحة: |
https://doi.org/10.5603/MRJ.a2020.0006Test
https://journals.viamedica.pl/medical_research_journal/article/view/MRJ.a2020.0006Test |
| حقوق: |
Completion of the online submission form electronically is tantamount to automatically and free-of-charge transferring of the copyright for publishing and distribution of the submitted material (in all known now and developed in the future forms and fields of exploitation) to the Publisher, under condition that those materials are accepted for publication. The authors agree not to publish any data or figures presented in their work anywhere and in any language without the prior written consent of the owner of the copyrights, i.e. the Publisher. |
| رقم الانضمام: |
edsbas.E6F2B9FC |
| قاعدة البيانات: |
BASE |
