التفاصيل البيبلوغرافية
| العنوان: |
Stereotactic radiotherapy for brain oligometastases |
| المؤلفون: |
Lupattelli, Marco, Tini, Paolo, Nardone, Valerio, Aristei, Cynthia, Borghesi, Simona, Maranzano, Ernesto, Anselmo, Paola, Ingrosso, Gianluca, Deantonio, Letizia, Buglione di Monale e Bastia, Michela |
| المصدر: |
Reports of Practical Oncology and Radiotherapy; Vol 27, No 1 (2022); 15-22 |
| بيانات النشر: |
Via Medica |
| سنة النشر: |
2022 |
| المجموعة: |
Via Medica Journals |
| مصطلحات موضوعية: |
stereotactic radiotherapy, radiosurgery, oligometastasis, brain metastases, hypofractionation, local control, toxicity, radionecrosis |
| الوصف: |
Brain metastases, the most common metastases in adults, will develop in up to 40% of cancer patients, accounting for more than one-half of all intracranial tumors. They are most associated with breast and lung cancer, melanoma and, less frequently, colorectal and kidney carcinoma. MRI is the gold standard for diagnosis. For the treatment plan, CT images are co-registered and fused with a gadolinium-enhanced T1-weighted MRI where tumor volume and organs at risk are contoured. Alternatively, plain and contrast-enhanced CT scans are co-registered. Single-fraction stereotactic radiotherapy (SRT) is used to treat patients with good performance status and up to 4 lesions with a diameter of 30 mm or less that are distant from crucial brain function areas. Fractionated SRT (2–5 fractions) is used for larger lesions, in eloquent areas or in proximity to crucial or surgically inaccessible areas and to reduce treatment-related neurotoxicity. The single-fraction SRT dose, which depends on tumor diameter, impacts local control. Fractionated SRT may encompass different schedules. No randomized trial data compared the safety and efficacy of single and multiple fractions. Both single-fraction and fractionated SRT provide satisfactory local control rates, tolerance, a low risk of transient acute adverse events and of radiation necrosis the incidence of which correlated with the irradiated brain volume. |
| نوع الوثيقة: |
other/unknown material |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
https://journals.viamedica.pl/rpor/article/view/RPOR.a2021.0133Test |
| DOI: |
10.5603/RPOR.a2021.0133 |
| الإتاحة: |
https://doi.org/10.5603/RPOR.a2021.0133Test
https://journals.viamedica.pl/rpor/article/view/RPOR.a2021.0133Test |
| حقوق: |
Completion of the online submission form electronically (the Author's Statement) is tantamount to automatic transfer of the copyright for publishing and distribution of the submitted material (in all current and future forms and fields of exploitation) to the Copyright Owner, i.e. Greater Poland Cancer Centre (Poznan, Poland), on condition that these materials are accepted for publication. The authors agree not to publish any data or figures presented in their work in any place or in any language without the prior written consent of the Publisher. |
| رقم الانضمام: |
edsbas.825F19A0 |
| قاعدة البيانات: |
BASE |
