دورية أكاديمية
Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis
| العنوان: | Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis |
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| المؤلفون: | Gilles, Greg, Vohra, Arjun, Robles, Dagoberto, Taljanovic, Mihra S, Ashbeck, Erin L, Caruso, Chelsea, Duryea, Jeffrey, Bedrick, Edward J, Guermazi, Ali, Kwoh, C Kent |
| المصدر: | Radiology Research and Scholarship |
| بيانات النشر: | UNM Digital Repository |
| سنة النشر: | 2023 |
| المجموعة: | UNM Digital Repository (The University of New Mexico) |
| مصطلحات موضوعية: | MRI, biomarkers, effusion, inflammation, knee, osteoarthritis, quantitative imaging, semi-automated, synovitis |
| الوصف: | Effusion-synovitis (ES) is recognized as a component of osteoarthritis, creating a need for rapid methods to assess ES on MRI. We describe the development and reliability of an efficient single-slice semi-automated quantitative approach to measure ES. We used two samples from the Osteoarthritis Initiative (OAI): 50 randomly selected OAI participants with radiographic osteoarthritis (i.e., Kellgren-Lawrence (KL) grade 2 or 3) and a subset from the Foundation for the National Institutes of Health Osteoarthritis Biomarker study. An experienced musculoskeletal radiologist trained four non-expert readers to use custom semi-automated software to measure ES on a single axial slice and then read scans blinded to prior assessments. The estimated intraclass correlation coefficient (ICC) for intra-reader reliability of the single-slice ES method in the KL 2-3 sample was 0.96 (95% CI: 0.93, 0.97), and for inter-reader reliability, the ICC was 0.90 (95% CI: 0.87, 0.95). The intra-reader mean absolute difference (MAD) was 35 mm3 (95% CI: 28, 44), and the inter-reader MAD was 61 mm3 (95% CI: 48, 76). Our single-slice quantitative knee ES measurement offers a reliable, valid, and efficient surrogate for multi-slice quantitative and semi-quantitative assessment. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | https://digitalrepository.unm.edu/rad_pubs/18Test; https://digitalrepository.unm.edu/context/rad_pubs/article/1015/viewcontent/jcm_12_02691.pdfTest |
| DOI: | 10.3390/jcm12072691 |
| الإتاحة: | https://doi.org/10.3390/jcm12072691Test https://digitalrepository.unm.edu/rad_pubs/18Test https://digitalrepository.unm.edu/context/rad_pubs/article/1015/viewcontent/jcm_12_02691.pdfTest |
| رقم الانضمام: | edsbas.22BFE7F8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/jcm12072691 |
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