التفاصيل البيبلوغرافية
| العنوان: |
Retinoblastoma, the visible CNS tumor: A review. |
| المؤلفون: |
Dimaras, H, Corson, TW |
| بيانات النشر: |
University of Nairobi |
| سنة النشر: |
2018 |
| المجموعة: |
University of Nairobi Digital Repository |
| مصطلحات موضوعية: |
MYCN, cancer genetics, neuroimaging, optical coherence tomography, pediatric cancer, pineoblastoma |
| الوصف: |
The pediatric ocular cancer retinoblastoma is the only central nervous system (CNS) tumor readily observed without specialized equipment: it can be seen by, and in, the naked eye. This accessibility enables unique imaging modalities. Here, we review this cancer for a neuroscience audience, highlighting these clinical and research imaging options, including fundus imaging, optical coherence tomography, ultrasound, and magnetic resonance imaging. We also discuss the subtype of retinoblastoma driven by the MYCN oncogene more commonly associated with neuroblastoma, and consider trilateral retinoblastoma, in which an intracranial tumor arises along with ocular tumors in patients with germline RB1 gene mutations. Retinoblastoma research and clinical care can offer insights applicable to CNS malignancies, and also benefit from approaches developed elsewhere in the CNS. |
| نوع الوثيقة: |
other/unknown material |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Dimaras, Helen, and Timothy W. Corson. "Retinoblastoma, the visible CNS tumor: A review." Journal of Neuroscience Research.; https://www.ncbi.nlm.nih.gov/pubmed/29314142Test; http://hdl.handle.net/11295/102340Test |
| الإتاحة: |
http://hdl.handle.net/11295/102340Test
https://www.ncbi.nlm.nih.gov/pubmed/29314142Test |
| حقوق: |
Attribution-NonCommercial-NoDerivs 3.0 United States ; http://creativecommons.org/licenses/by-nc-nd/3.0/usTest/ |
| رقم الانضمام: |
edsbas.42CE4F2C |
| قاعدة البيانات: |
BASE |
