دورية أكاديمية
Collateral Circulation and Outcome in Atherosclerotic Versus Cardioembolic Cerebral Large Vessel Occlusion
| العنوان: | Collateral Circulation and Outcome in Atherosclerotic Versus Cardioembolic Cerebral Large Vessel Occlusion |
|---|---|
| المؤلفون: | Guglielmi, Valeria, LeCouffe, Natalie E., Zinkstok, Sanne M., Compagne, Kars C. J., Eker, Reyhan, Treurniet, Kilian M., Tolhuisen, Manon L., van der Worp, H. Bart, Jansen, Ivo G. H., van Oostenbrugge, Robert J., Marquering, Henk A., Dippel, Diederik W. J., Emmer, Bart J., Majoie, Charles B. L. M., Roos, Yvo B. W. E. M., Coutinho, Jonathan M. |
| المصدر: | MR CLEAN Registry Investigators , Guglielmi , V , LeCouffe , N E , Zinkstok , S M , Compagne , K C J , Eker , R , Treurniet , K M , Tolhuisen , M L , van der Worp , H B , Jansen , I G H , van Oostenbrugge , R J , Marquering , H A , Dippel , D W J , Emmer , B J , Majoie , C B L M , Roos , Y B W E M & Coutinho , J M 2019 , ' Collateral Circulation and .... |
| سنة النشر: | 2019 |
| المجموعة: | University of Groningen research database |
| مصطلحات موضوعية: | atherothrombotic stroke, cardiac emboli, collateral circulation, endovascular treatment, ischemic stroke, ACUTE ISCHEMIC-STROKE, ATRIAL-FIBRILLATION, CT ANGIOGRAPHY, UNDETERMINED SOURCE, EMBOLIC STROKES, FEATURES, CLASSIFICATION, HYPOPERFUSION, THROMBECTOMY, ETIOLOGY |
| الوصف: | Background and Purpose-Due to chronic hypoperfusion, cervical atherosclerosis may promote cerebral collateral circulation. We hypothesized that patients with ischemic stroke due to cervical carotid atherosclerosis have a more extensive collateral circulation and better outcomes than patients with cardioembolism. We tested this hypothesis in a population of patients who underwent endovascular treatment for large vessel occlusion. Methods-From the MR-CLEAN Registry (Multicenter Randomized Controlled Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands), we selected consecutive adult endovascular treatment patients (March 2014 to June 2016) with acute ischemic stroke due to anterior circulation large vessel occlusion and compared patients with cervical carotid artery stenosis >50% to those with cardioembolic etiology. The primary outcome was collateral score, graded on a 4-point scale. Secondary outcomes included the modified Rankin Scale (mRS) score and mortality at 90 days. We performed multivariable regression analyses and adjusted for potential confounders. Results-Of 1627 patients in the Registry, 190 patients with cervical carotid atherosclerosis and 476 with cardioembolism were included. Patients with cervical carotid atherosclerosis were younger (median 69 versus 76 years, P Conclusions-Patients with stroke due to cervical carotid atherosclerosis had a more extensive cerebral collateral circulation and a slightly better median mRS at 90 days than patients with cardioembolic stroke. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://research.rug.nl/en/publications/d649fafd-9ddc-43b4-95e1-16fc7e1b0a50Test |
| DOI: | 10.1161/STROKEAHA.119.026299 |
| الإتاحة: | https://doi.org/10.1161/STROKEAHA.119.026299Test https://hdl.handle.net/11370/d649fafd-9ddc-43b4-95e1-16fc7e1b0a50Test https://research.rug.nl/en/publications/d649fafd-9ddc-43b4-95e1-16fc7e1b0a50Test https://pure.rug.nl/ws/files/117209147/Collateral_Circulation_and_Outcome_in_Atherosclerotic_Versus_Cardioembolic_Cerebral_Large_Vessel_Occlusion.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.35B39CC5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1161/STROKEAHA.119.026299 |
|---|