-
1دورية أكاديمية
المصدر: Goodwin , M L , Gladden , L B & Nijsten , M W N 2020 , ' Lactate-Protected Hypoglycemia (LPH) ' , Frontiers in Neuroscience , vol. 14 , 920 . https://doi.org/10.3389/fnins.2020.00920Test
مصطلحات موضوعية: lactate, hypoglycemia, shuttle, hyperlactatemia, monocarboxylate transporter, lactate dehydrogenase, AEROBIC GLYCOLYSIS, METABOLISM, GLUCOSE, CANCER, CELLS, PATIENT, CONTEXT, ENERGY, TUMORS, BRAIN
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.3389/fnins.2020.00920Test
https://hdl.handle.net/11370/19cffd0f-0c76-4ac6-a30b-9b1affec61f4Test
https://research.rug.nl/en/publications/19cffd0f-0c76-4ac6-a30b-9b1affec61f4Test
https://pure.rug.nl/ws/files/159342206/fnins_14_00920.pdfTest -
2دورية أكاديمية
المؤلفون: Deckers, E A, Kruijff, S, Brouwers, A H, van der Steen, K, Hoekstra, H J, Thompson, J F, Vállez García, David, Wevers, K P
المصدر: Deckers , E A , Kruijff , S , Brouwers , A H , van der Steen , K , Hoekstra , H J , Thompson , J F , Vállez García , D & Wevers , K P 2020 , ' The association between active tumor volume, total lesion glycolysis and levels of S-100B and LDH in stage IV melanoma patients ' , European Journal of Surgical Oncology , vol. 46 , no. 11 , pp. 2147-2153 . https://doi.org/10.1016/j.ejso.2020.07.011Test
مصطلحات موضوعية: Melanoma, PET, Biomarkers, S-100B, LDH, Staging, FDG-PET/CT, LACTATE-DEHYDROGENASE, MALIGNANT-MELANOMA, SERUM S-100B, SURVIVAL, GUIDELINES, IPILIMUMAB, DIAGNOSIS, PROTEIN, ASSAYS
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1016/j.ejso.2020.07.011Test
https://hdl.handle.net/11370/2b02e666-5947-499c-b576-a401e4a08c07Test
https://research.rug.nl/en/publications/2b02e666-5947-499c-b576-a401e4a08c07Test
https://pure.rug.nl/ws/files/156760140/The_association_between_active_tumor_volume_total_lesion_glycolysis_and_levels_of_S_100B_and_LDH_in_stage_IV_melanoma_patients.pdfTest -
3دورية أكاديمية
المصدر: Nguyen , K T T , Frijlink , H W & Hinrichs , W L J 2020 , ' Inhomogeneous Distribution of Components in Solid Protein Pharmaceuticals : Origins, Consequences, Analysis, and Resolutions ' , Journal of Pharmaceutical Sciences , vol. 109 , no. 1 , pp. 134-153 . https://doi.org/10.1016/j.xphs.2019.10.010Test
مصطلحات موضوعية: phase separation(s), freeze-drying, spray drying, protein formulation(s), stability, solid-state, analysis, imaging method(s), spectroscopy, AMORPHOUS PHASE-SEPARATION, HUMAN GROWTH-HORMONE, NEAR-INFRARED SPECTROSCOPY, GLASS-TRANSITION TEMPERATURES, DRYING-INDUCED VARIATIONS, ATOMIC-FORCE MICROSCOPY, RAY-POWDER DIFFRACTION, STORAGE STABILITY, LACTATE-DEHYDROGENASE, FREEZE-CONCENTRATION
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1016/j.xphs.2019.10.010Test
https://hdl.handle.net/11370/9ab1993a-9d57-480f-94ff-4a7f02f99df6Test
https://research.rug.nl/en/publications/9ab1993a-9d57-480f-94ff-4a7f02f99df6Test
https://pure.rug.nl/ws/files/117125702/1_s2.0_S0022354919306458_main.pdfTest -
4دورية أكاديمية
المؤلفون: Blais-Lecours, Pascale, Laouafa, Sofien, Arias-Reyes, Christian, Santos, Webster L., Joseph, Vincent, Burgess, Janette K., Halayko, Andrew J., Soliz, Jorge, Marsolais, David
المصدر: Blais-Lecours , P , Laouafa , S , Arias-Reyes , C , Santos , W L , Joseph , V , Burgess , J K , Halayko , A J , Soliz , J & Marsolais , D 2020 , ' Metabolic Adaptation of Airway Smooth Muscle Cells to an SPHK2 Substrate Precedes Cytostasis ' , American Journal of Respiratory Cell and Molecular Biology , vol. 62 , no. 1 , pp. 35-42 . https://doi.org/10.1165/rcmb.2018-0397OCTest
مصطلحات موضوعية: AAL-R, Asthma, FTY720, Metabolism, Sphingolipids, airway smooth muscle cell, article, bronchus hyperreactivity, cell proliferation, controlled study, cytostasis, enzyme activity, gene expression, human cell, oxidative phosphorylation, protein expression, protein function, stroma cell, endogenous compound, fingolimod, Ki 67 antigen, lactate dehydrogenase, oxygen, sphingolipid, sphingosine, sphingosine kinase 2, tetrazolium
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1165/rcmb.2018-0397OCTest
https://hdl.handle.net/11370/c887ae2b-5e96-4a84-b942-a07695cbbfaaTest
https://research.rug.nl/en/publications/c887ae2b-5e96-4a84-b942-a07695cbbfaaTest
https://pure.rug.nl/ws/files/95015256/Metabolic_adaptation_of_airway_smooth_muscle_cells_to_a_SPHK2_substrate_precedes_cytostasis.pdfTest -
5دورية أكاديمية
المؤلفون: Grasmeijer, Niels, Tiraboschi, Valeria, Woerdenbag, Herman J, Frijlink, Henderik W, Hinrichs, Wouter L J
المصدر: Grasmeijer , N , Tiraboschi , V , Woerdenbag , H J , Frijlink , H W & Hinrichs , W L J 2019 , ' Identifying critical process steps to protein stability during spray drying using a vibrating mesh or a two-fluid nozzle ' , European Journal of Pharmaceutical Sciences , vol. 128 , pp. 152-157 . https://doi.org/10.1016/j.ejps.2018.11.027Test
مصطلحات موضوعية: Spray drying, L-Lactic dehydrogenase, Enzymatic activity, Twofluid nozzle, Vibrating mesh nozzle, LACTATE-DEHYDROGENASE, NATIVE STRUCTURE, STABILIZATION, JET, PRESERVATION, NEBULIZATION, MECHANISMS, TREHALOSE, STORAGE, SUGARS
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1016/j.ejps.2018.11.027Test
https://hdl.handle.net/11370/e7ff696c-7361-48d9-925f-2fbbfdcb0877Test
https://research.rug.nl/en/publications/e7ff696c-7361-48d9-925f-2fbbfdcb0877Test
https://pure.rug.nl/ws/files/71887805/1_s2.0_S0928098718305189_main.pdfTest -
6دورية أكاديمية
المصدر: Ewing , T A , Fraaije , M W , Mattevi , A & van Berkel , W J H 2017 , ' The VAO/PCMH flavoprotein family ' , Archives of Biochemistry and Biophysics , vol. 632 , pp. 104-117 . https://doi.org/10.1016/j.abb.2017.06.022Test
مصطلحات موضوعية: enzyme mechanism, flavoprotein, oxidoreductase, phylogeny, protein family, VANILLYL-ALCOHOL OXIDASE, GAMMA-LACTONE DEHYDROGENASE, VITAMIN-C BIOSYNTHESIS, N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE, COVALENTLY-BOUND FLAVIN, D-LACTATE DEHYDROGENASE, MYCOBACTERIUM-TUBERCULOSIS DPRE1, MAIZE CYTOKININ DEHYDROGENASE, HYDROXYLASE GENES EHYA/EHYB, PENICILLIUM-CYANEO-FULVUM
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1016/j.abb.2017.06.022Test
https://hdl.handle.net/11370/d01ce50d-c4d0-48fe-a95e-dbbed8cdc8deTest
https://research.rug.nl/en/publications/d01ce50d-c4d0-48fe-a95e-dbbed8cdc8deTest
https://pure.rug.nl/ws/files/50053971/1_s2.0_S0003986117303600_main.pdfTest -
7دورية أكاديمية
المؤلفون: Mensink, Maarten A, Frijlink, Henderik W, van der Voort Maarschalk, Kees, Hinrichs, Wouter L J
المصدر: Mensink , M A , Frijlink , H W , van der Voort Maarschalk , K & Hinrichs , W L J 2017 , ' How sugars protect proteins in the solid state and during drying (review) : Mechanisms of stabilization in relation to stress conditions ' , European Journal of Pharmaceutics and Biopharmaceutics , vol. 114 , pp. 288-295 . https://doi.org/10.1016/j.ejpb.2017.01.024Test
مصطلحات موضوعية: Biologicals, Storage stability, Temperature, Water activity, Vitrification, Mobility, Degradation, MINI FREEZE-DRYER, CHEMICAL-STABILITY, LACTATE-DEHYDROGENASE, LYOPHILIZED FORMULATIONS, INFRARED-SPECTROSCOPY, THERAPEUTIC PROTEINS, DRIED PROTEINS, AGGREGATION, GLASSES
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1016/j.ejpb.2017.01.024Test
https://hdl.handle.net/11370/2acaf0d9-8867-45ab-941a-77257a8fde1eTest
https://research.rug.nl/en/publications/2acaf0d9-8867-45ab-941a-77257a8fde1eTest
https://pure.rug.nl/ws/files/42077476/How_sugars_protect_proteins_in_the_solid_state_and_during_drying.pdfTest -
8دورية أكاديمية
المؤلفون: Neves, A.R., Pool, W., Solopova, A., Kok, J., Santos, H, Kuipers, O.P.
المصدر: Neves , A R , Pool , W , Solopova , A , Kok , J , Santos , H & Kuipers , O P 2010 , ' Towards Enhanced Galactose Utilization by Lactococcus lactis ' , Applied and environmental microbiology , vol. 76 , no. 21 , pp. 7048 - 7060 . https://doi.org/10.1128/AEM.01195-10Test
مصطلحات موضوعية: DEPENDENT PHOSPHOTRANSFERASE SYSTEM, TAGATOSE 6-PHOSPHATE PATHWAY, CONTROLLED GENE-EXPRESSION, GRAM-POSITIVE BACTERIA, SUBSP CREMORIS MG1363, STREPTOCOCCUS-LACTIS, ACID BACTERIA, IN-VIVO, CARBOHYDRATE-METABOLISM, LACTATE-DEHYDROGENASE
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1128/AEM.01195-10Test
https://hdl.handle.net/11370/d038d652-44cf-44e4-a6d7-b03bc6eb916fTest
https://research.rug.nl/en/publications/d038d652-44cf-44e4-a6d7-b03bc6eb916fTest
https://pure.rug.nl/ws/files/10437507/2010ApplEnvirMicrobiolNeves.pdfTest -
9دورية أكاديمية
المؤلفون: Neves, Ana R., Pool, Wietske A., Castro, Rute, Mingote, Ana, Santos, Filipe, Kok, Jan, Kuipers, Oscar P., Santos, Helena
المصدر: Neves , A R , Pool , W A , Castro , R , Mingote , A , Santos , F , Kok , J , Kuipers , O P & Santos , H 2006 , ' The alpha-phosphoglucomutase of Lactococcus lactis is unrelated to the alpha-D-phosphohexomutase superfamily and is encoded by the essential gene pgmH ' , The Journal of Biological Chemistry , vol. 281 , no. 48 , pp. 36864-36873 . https://doi.org/10.1074/jbc.M607044200Test
مصطلحات موضوعية: NUCLEAR-MAGNETIC-RESONANCE, IN-VIVO, ACID BACTERIA, EXOPOLYSACCHARIDE BIOSYNTHESIS, BETA-PHOSPHOGLUCOMUTASE, LIPOPOLYSACCHARIDE BIOSYNTHESIS, CELLULAR PHOSPHOGLUCOMUTASE, STREPTOCOCCUS-PNEUMONIAE, LACTATE-DEHYDROGENASE, GALACTOSE UTILIZATION
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1074/jbc.M607044200Test
https://hdl.handle.net/11370/111d66bc-ccce-4ec2-ba9e-1ac6e3effb84Test
https://research.rug.nl/en/publications/111d66bc-ccce-4ec2-ba9e-1ac6e3effb84Test
https://pure.rug.nl/ws/files/6701131/2006JBiolChemNevesSupp.pdfTest
https://pure.rug.nl/ws/files/6701132/2006JBiolChemNeves.pdfTest -
10دورية أكاديمية
المؤلفون: Westerkamp, A.C., De Jong, I., Nijsten, M.W., Leuvenink, H.G.D., Touw, D.J., Lisman, T., Moshage, H., Porte, R.J.
المصدر: Westerkamp , A C , De Jong , I , Nijsten , M W , Leuvenink , H G D , Touw , D J , Lisman , T , Moshage , H & Porte , R J 2016 , ' Pre-and postconditioning effects of metformin in rat donor livers ' , HPB , vol. 18 , pp. 546-547 .
مصطلحات موضوعية: metformin, marker, gamma glutamyltransferase, glucose, bicarbonate, bilirubin, lactate dehydrogenase, caspase 3, adenosine triphosphate, thiobarbituric acid reactive substance, rat, donor, liver, injury, preservation, liquid, perfusion, liver resection, feeding, transplantation, bile, machine