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1دورية أكاديمية
المؤلفون: Jorge, Pedro Freire, Goodwin, Matthew L., Renes, Maurits H., Nijsten, Maarten W., Pamenter, Matthew
المصدر: Jorge , P F , Goodwin , M L , Renes , M H , Nijsten , M W & Pamenter , M 2022 , ' Low Cancer Incidence in Naked Mole-Rats May Be Related to Their Inability to Express the Warburg Effect ' , Frontiers in Physiology , vol. 13 , 859820 . https://doi.org/10.3389/fphys.2022.859820Test
مصطلحات موضوعية: metabolism, Warburg effect, naked mole-rat, cancer metabolism, metabolic fuel switching, hypoxic metabolic response, hypoxic ventilatory response (HVR), thermoregulation, LACTATE ACCUMULATION, END-PRODUCT, OXYGEN, PERSPECTIVE, ANOXIA, MODEL, SHELL, CYCLE
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.3389/fphys.2022.859820Test
https://hdl.handle.net/11370/55023bd0-74ff-4107-a8ec-bfded7e40e29Test
https://research.rug.nl/en/publications/55023bd0-74ff-4107-a8ec-bfded7e40e29Test
https://pure.rug.nl/ws/files/227245687/fphys_13_859820.pdfTest -
2دورية أكاديمية
المؤلفون: Hu, Dongjian, Linders, Annet, Yamak, Abir, Correia, Claudia, Kijlstra, Jan David, Garakani, Arman, Xiao, Ling, Milan, David J., van der Meer, Peter, Serra, Margarida, Alves, Paula M., Domian, Ibrahim J.
المصدر: Hu , D , Linders , A , Yamak , A , Correia , C , Kijlstra , J D , Garakani , A , Xiao , L , Milan , D J , van der Meer , P , Serra , M , Alves , P M & Domian , I J 2018 , ' Metabolic Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes by Inhibition of HIF1 alpha and LDHA ' , Circulation Research , vol. 123 , no. 9 , pp. 1066-1079 . https://doi.org/10.1161/CIRCRESAHA.118.313249Test
مصطلحات موضوعية: glucose, glycolysis, hypoxia-inducible factor 1, metabolism, myocytes, oxidative phosphorylation, stem cells, HYPOXIA-INDUCIBLE FACTORS, FUNCTIONAL MATURATION, TRANSCRIPTION FACTOR, CANCER METABOLISM, CARDIAC MYOCYTES, FACTOR 1-ALPHA, ADULT, HEART, FORCE, DIFFERENTIATION
الإتاحة: https://doi.org/10.1161/CIRCRESAHA.118.313249Test
https://hdl.handle.net/11370/c2e8a168-eee1-4898-8758-fa045e1d8983Test
https://research.rug.nl/en/publications/c2e8a168-eee1-4898-8758-fa045e1d8983Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208155Test -
3دورية أكاديمية
المؤلفون: Adam, Isabell, Dewi, Dyah L., Mooiweer, Joram, Sadik, Ahmed, Mohapatra, Soumya R., Berdel, Bianca, Keil, Melanie, Sonner, Jana K., Thedieck, Kathrin, Rose, Adam J., Platten, Michael, Heiland, Ines, Trump, Saskia, Opitz, Christiane A.
المصدر: Adam , I , Dewi , D L , Mooiweer , J , Sadik , A , Mohapatra , S R , Berdel , B , Keil , M , Sonner , J K , Thedieck , K , Rose , A J , Platten , M , Heiland , I , Trump , S & Opitz , C A 2018 , ' Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation ' , OncoImmunology , vol. 7 , no. 12 , 1486353 . https://doi.org/10.1080/2162402X.2018.1486353Test
مصطلحات موضوعية: Indoleamine-2, 3-dioxygenase, tryptophan-2, tumor, proliferation, cancer metabolism, tryptophan, tRNA synthetase, immunosuppression, nutrients, starvation, immunosurveillance, inflammation and cancer, TUMORAL IMMUNE RESISTANCE, ARYL-HYDROCARBON RECEPTOR, AMINO-ACID TRANSPORTER, INDOLEAMINE 2,3-DIOXYGENASE, T-CELLS, TRANSLATIONAL CONTROL, RESPONSE PATHWAY, EPITHELIAL-CELLS, MAMMALIAN-CELLS, GENE-EXPRESSION
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1080/2162402X.2018.1486353Test
https://hdl.handle.net/11370/5a66a80a-9fd2-4ca7-a2f4-5150526fd88bTest
https://research.rug.nl/en/publications/5a66a80a-9fd2-4ca7-a2f4-5150526fd88bTest
https://pure.rug.nl/ws/files/71536569/Upregulation_of_tryptophanyl_tRNA_synthethase_adapts_human_cancer_cells_to_nutritional_stress_caused_by_tryptophan_degradation.pdfTest -
4دورية أكاديمية
المؤلفون: Xu, Pan, Oosterveer, Maaike H., Stein, Sokrates, Demagny, Hadrien, Ryu, Dongryeol, Moullan, Norman, Wang, Xu, Can, Emine, Zamboni, Nicola, Comment, Arnaud, Auwerx, Johan, Schoonjans, Kristina
المصدر: Xu , P , Oosterveer , M H , Stein , S , Demagny , H , Ryu , D , Moullan , N , Wang , X , Can , E , Zamboni , N , Comment , A , Auwerx , J & Schoonjans , K 2016 , ' LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer ' , Genes & Development , vol. 30 , no. 11 , pp. 1255-1260 . https://doi.org/10.1101/gad.277483.116Test
مصطلحات موضوعية: Hepatocellular carcinoma, cancer metabolism, nuclear receptor NR5A2, mitochondria, anaplerosis, mTOR, NADPH, RECEPTOR HOMOLOG-1, CELL-GROWTH, IN-VIVO, METABOLISM, PROLIFERATION, LRH-1, LIPOGENESIS, DEFICIENCY, PATHWAY, BIOLOGY
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1101/gad.277483.116Test
https://hdl.handle.net/11370/c34317e6-6095-4bc9-a14a-26377213ca41Test
https://research.rug.nl/en/publications/c34317e6-6095-4bc9-a14a-26377213ca41Test
https://pure.rug.nl/ws/files/40762913/LRH_1_dependent_programming_of_mitochondrial_glutamine_processing_drives_liver_cancer.pdfTest -
5دورية أكاديمية
المؤلفون: Masini, Tiziana, Birkaya, Barbara, van Dijk, Simon, Mondal, Milon, Hekelaar, Johan, Jager, Manuel, van Scheltinga, Anke C. Terwisscha, Patel, Mulchand S., Hirsch, Anna K. H., Moman, Edelmiro
المصدر: Masini , T , Birkaya , B , van Dijk , S , Mondal , M , Hekelaar , J , Jager , M , van Scheltinga , A C T , Patel , M S , Hirsch , A K H & Moman , E 2016 , ' Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site ' , Journal of enzyme inhibition and medicinal chemistry , vol. 31 (S4) , pp. 170-175 . https://doi.org/10.1080/14756366.2016.1201812Test
مصطلحات موضوعية: Cancer metabolism, DCA, dichloroacetate, PDC, PDK2 inhibitors, pyruvate, CANCER-CELLS, METABOLISM, MECHANISMS, PHOSPHORYLATION, HYPOXIA, COMPLEX
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1080/14756366.2016.1201812Test
https://hdl.handle.net/11370/76919835-c6d6-43a6-a56d-90c7f9175723Test
https://research.rug.nl/en/publications/76919835-c6d6-43a6-a56d-90c7f9175723Test
https://pure.rug.nl/ws/files/78980585/Furoates_and_thenoates_inhibit_pyruvate_dehydrogenase_kinase_2_allosterically_by_binding.pdfTest
