دورية أكاديمية
Early pregnancy hemoglobin is associated with the risk of gestational diabetes mellitus:a retrospective cohort study
| العنوان: | Early pregnancy hemoglobin is associated with the risk of gestational diabetes mellitus:a retrospective cohort study |
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| المؤلفون: | Yong, Heng Yaw, Shariff, Zalilah Mohd, Yusof, Barakatun Nisak Mohd, Rejali, Zulida, Tee, Yvonne Yee Siang, Bindels, Jacques, van der Beek, Eline M. |
| المصدر: | Yong , H Y , Shariff , Z M , Yusof , B N M , Rejali , Z , Tee , Y Y S , Bindels , J & van der Beek , E M 2022 , ' Early pregnancy hemoglobin is associated with the risk of gestational diabetes mellitus : a retrospective cohort study ' , British Journal of Nutrition , vol. 128 , no. 11 , pp. 2097-2104 . https://doi.org/10.1017/S000711452100502XTest |
| سنة النشر: | 2022 |
| المجموعة: | University of Groningen research database |
| مصطلحات موضوعية: | Hg, Hb change, Gestational diabetes mellitus, Pregnancy, DIETARY IRON INTAKE, MATERNAL HEMOGLOBIN, PREVALENCE, WOMEN, ANEMIA, AGE, TRIMESTER, OVERLOAD |
| الوصف: | This study aimed to determine the association between hemoglobin (Hb) concentration and Hb change, during early to mid-pregnancy with the risk of gestational diabetes mellitus (GDM). This was a clinic-based retrospective cohort study of 1951 healthy pregnant women (18-45 years old) with a singleton gestation attending antenatal care at government health clinics. Hb concentration at first prenatal visit and each trimester was extracted from the antenatal cards. Hb changes from first prenatal visit to first and second trimester as well as from second to third trimester were calculated. Multivariate logistic regression was used with adjustment for covariates. Women with GDM had significantly higher Hb concentrations (Hb 1) at first prenatal visit (< 12 weeks) compared with non-GDM women (11 center dot 91 g/dl v.11 center dot 74 g/dl). Hb 1 and Hb changes (Hb change 2) from first prenatal visit to the second trimester (23-27th weeks) were significantly associated with GDM risk, with an adjusted OR of 1 center dot 14 (95 % CI 1 center dot 01, 1 center dot 29) and 1 center dot 25 (95 % CI 1 center dot 05, 1 center dot 49), respectively. The significant associations between Hb 1 and Hb change 2 with the risk of GDM were found among non-Malays, overweight/obese and women aged 35 years and above. Women with higher Hb concentrations in early pregnancy were at higher risk of GDM, and such association was significant among women aged 35 years and above, non-Malays and overweight/obese. This raises a potential concern for elevated Fe status in early pregnancy as a risk factor of GDM among Fe-replete women. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://research.rug.nl/en/publications/bd265205-3f49-4dcf-9d9a-d4b119a2d5f8Test |
| DOI: | 10.1017/S000711452100502X |
| الإتاحة: | https://doi.org/10.1017/S000711452100502XTest https://hdl.handle.net/11370/bd265205-3f49-4dcf-9d9a-d4b119a2d5f8Test https://research.rug.nl/en/publications/bd265205-3f49-4dcf-9d9a-d4b119a2d5f8Test https://pure.rug.nl/ws/files/587528261/early_pregnancy_hemoglobin_is_associated_with_the_risk_of_gestational_diabetes_mellitus_a_retrospective_cohort_study.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.A2B83910 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1017/S000711452100502X |
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