التفاصيل البيبلوغرافية
| العنوان: |
Effect of Simulated Geomagnetic Activity on Myocardial Ischemia/Reperfusion Injury in Rats |
| المؤلفون: |
Wu,Hui, Chang,Weiyu, Deng,Yanglin, Chen,Xinli, Ding,Yongli, Li,Xuesong, Dong,Liang |
| المصدر: |
Brazilian Journal of Cardiovascular Surgery v.34 n.6 2019 |
| بيانات النشر: |
Sociedade Brasileira de Cirurgia Cardiovascular |
| سنة النشر: |
2019 |
| المجموعة: |
SciELO Brazil (Scientific Electronic Library Online) |
| مصطلحات موضوعية: |
Hemodynamics, Myocardial Reperfusion Injury, Creatine Kinase, Troponin I, L-Lactate Dehydrogenase, Disease Outbreaks, Animal, Rats |
| الوصف: |
Objective: To study the response of myocardial ischemia/reperfusion injury (MI/RI) in rats to simulated geomagnetic activity. Methods: In a simulated strong geomagnetic outbreak, the MI/RI rat models were radiated, and their area of myocardial infarction, hemodynamic parameters, creatine kinase (CK), lactate dehydrogenase (LDH), melatonin, and troponin I values were measured after a 24-hour intervention. Results: Our analysis indicates that the concentrations of troponin I in the geomagnetic shielding+operation group were lower than in the radiation+operation group (P<0.05), the concentrations of melatonin in the shielding+operation group and normal+operation group were higher than in the radiation + operation group (P<0.01), and the concentrations of CK in the shielding + operation group were lower than in the radiation + operation group and normal + operation group (P<0.05). Left ventricular developed pressure (LVDP) and ± dP/dtmax in the radiation+operation group were lower than in the shielding + operation group and normal+operation group (P<0.01). Left ventricular end-diastolic pressure (LEVDP) in the shielding + operation group was higher than in the normal + operation group (P<0.05). There was no significant difference in area of myocardial infarction and LDH between the shielding + operation group and the radiation + operation group. Conclusion: Our data suggest that geomagnetic activity is important in regulating myocardial reperfusion injury. The geomagnetic shielding has a protective effect on myocardial injury, and the geomagnetic radiation is a risk factor for aggravating the cardiovascular and cerebrovascular diseases. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
text/html |
| اللغة: |
English |
| الإتاحة: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000600006Test |
| حقوق: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.E6CAF309 |
| قاعدة البيانات: |
BASE |
