دورية أكاديمية
Human Immunodeficiency Virus Nephropathy in Central Africa: The Value of Renal Ultrasound
| العنوان: | Human Immunodeficiency Virus Nephropathy in Central Africa: The Value of Renal Ultrasound |
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| المؤلفون: | Kinfuidi, Nancy Moyo, Bompeka, François Lepira, Mangani, Nazaire Nseka, Kalambayi, Patrick Kayembe, Dikamba, Nelly, Kisile, Olive, Aloni, Michel, Mfutu, Pepe Ekulu, Tshibola, Jean Mukaya, Tshikwela, Michel Lelo |
| المصدر: | Research in Health Science; Vol 4, No 1 (2019); p54 ; 2470-6213 ; 2470-6205 |
| بيانات النشر: | SCHOLINK CO.,LTD |
| سنة النشر: | 2019 |
| المجموعة: | Scholink Journals |
| الوصف: | Introduction: HIV-Associated Nephropathy may shorten the life expectancy of affected patients. Its early detection is beneficial for the indication of treatment and hence prevention of progression to the end-stage of renal failure. The final diagnosis requires renal biopsy which may be difficult in some African area; clinical and ultrasound criteria may be helpful. The aim of this study was twofold: to characterize renal sonographic changes in HIV-positive patients with HIV associated Nephropathy and to investigate the correlation between renal sonographic changes and histological lesions in central Africa.Methods: A prospective and multi-center study conducted from January 2013 to July 2015 included, for renal ultrasound evaluation of the length, thickness and echogenicity, forty two of the 334 biologically confirmed HIV-positive patients who presented with significant proteinuria suggestive of HIV associated Nephropathy. And transcutaneous renal biopsy with histopathology has been performed in 16 patients of them. Statistical analyzes were used.Results: There were 100 men and 234 women; proteinuria was positive in 42 patients, (12.6%). The average length of the kidneys was 111 ± 8 mm (normal), with 10% of patients with pathological values (5% with kidneys of reduced size and 5%, increased size). The kidneys had an average thickness of 44 ± 5 mm (normal), with 21% of patients presenting an increase in renal thickness. Quantitative echogenicity was calculated at 1.492 ± 0.793 (normal), with 79% of patients with increased quantitative echogenicity. Of the 16 patients biopsied, all had tubulo-interstitial lesions, and 75% of them associated with glomerular lesions. In simple correlation analysis, tubular dilatation was positively and significantly related to quantitative echogenicity (r = 0.67, p < 0.01) and to renal parenchyma thickness (r = 0.67; 0.85, p ? 0.05). The relationship between the other parameters studied did not reach statistical significance. In multiple linear regression, glomerular hyalinosis, ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://www.scholink.org/ojs/index.php/rhs/article/view/1854/2015Test; http://www.scholink.org/ojs/index.php/rhs/article/view/1854Test |
| DOI: | 10.22158/rhs.v4n1p54 |
| الإتاحة: | https://doi.org/10.22158/rhs.v4n1p54Test http://www.scholink.org/ojs/index.php/rhs/article/view/1854Test |
| حقوق: | Copyright (c) 2019 Nancy Moyo Kinfuidi, François Lepira Bompeka, Nazaire Nseka Mangani, Patrick Kayembe Kalambayi, Nelly Dikamba, Olive Kisile, Michel Aloni, Pepe Ekulu Mfutu, Jean Mukaya Tshibola, Michel Lelo Tshikwela ; http://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: | edsbas.6AEC7B43 |
| قاعدة البيانات: | BASE |
| DOI: | 10.22158/rhs.v4n1p54 |
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