دورية أكاديمية
Electrochemical Detection of Pyocyanin as a Biomarker for Pseudomonas aeruginosa :A Focused Review
العنوان: | Electrochemical Detection of Pyocyanin as a Biomarker for Pseudomonas aeruginosa :A Focused Review |
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المؤلفون: | Alatraktchi, Fatima AlZahraa, Svendsen, Winnie Edith, Molin, Søren |
المصدر: | Alatraktchi , F A , Svendsen , W E & Molin , S 2020 , ' Electrochemical Detection of Pyocyanin as a Biomarker for Pseudomonas aeruginosa : A Focused Review ' , Sensors , vol. 20 , no. 18 , 5218 , pp. 1-15 . https://doi.org/10.3390/s20185218Test |
سنة النشر: | 2020 |
المجموعة: | Roskilde Universitets forskningsportal (RUC) / Roskilde University Research Portal |
مصطلحات موضوعية: | diagnosis, electrochemical detection, infections, pseudomonas aeruginosa, pyocyanin, voltammetry |
الوصف: | Pseudomonas aeruginosa (PA) is a pathogen that is recognized for its advanced antibiotic resistance and its association with serious diseases such as ventilator-associated pneumonia and cystic fibrosis. The ability to rapidly detect the presence of pathogenic bacteria in patient samples is crucial for the immediate eradication of the infection. Pyocyanin is one of PA’s virulence factors used to establish infections. Pyocyanin promotes virulence by interfering in numerous cellular functions in host cells due to its redox-activity. Fortunately, the redox-active nature of pyocyanin makes it ideal for detection with simple electrochemical techniques without sample pretreatment or sensor functionalization. The previous decade has seen an increased interest in the electrochemical detection of pyocyanin either as an indicator of the presence of PA in samples or as a tool for quantifying PA virulence. This review provides the first overview of the advances in electrochemical detection of pyocyanin and offers an input regarding the future directions in the field. |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | application/pdf |
اللغة: | English |
DOI: | 10.3390/s20185218 |
الإتاحة: | https://doi.org/10.3390/s20185218Test https://forskning.ruc.dk/da/publications/7fc6b315-a055-469f-80e8-59154c8419afTest https://hdl.handle.net/1800/7fc6b315-a055-469f-80e8-59154c8419afTest https://rucforsk.ruc.dk/ws/files/75256929/sensors_20_05218_5_.pdfTest |
حقوق: | info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsbas.452285EE |
قاعدة البيانات: | BASE |
DOI: | 10.3390/s20185218 |
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