المؤلفون: Samuelsen, Lisa, Holm, René, Schönbeck, Jens Christian Sidney

المصدر: Samuelsen , L , Holm , R & Schönbeck , J C S 2021 , ' Simultaneous determination of cyclodextrin stability constants as a function of pH and temperature – A tool for drug formulation and process design ' , Journal of Drug Delivery Science and Technology , vol. 65 , 102675 . https://doi.org/10.1016/j.jddst.2021.102675Test

مصطلحات موضوعية: Cyclodextrin, Binding constant, Temperature, pH, Model, Drug robustness, Equilibrium constant, Host-guest chemistry, Ionization, Surface plot, van't hoff equation

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016/j.jddst.2021.102675Test
https://forskning.ruc.dk/da/publications/f3da84bc-8543-4b8d-931d-68a6093e4099Test
https://hdl.handle.net/1800/f3da84bc-8543-4b8d-931d-68a6093e4099Test
https://rucforsk.ruc.dk/ws/files/78146006/1_s2.0_S1773224721003555_main.pdfTest

المؤلفون: Samuelsen, Lisa, Holm, René, Schönbeck, Jens Christian Sidney

المصدر: Samuelsen , L , Holm , R & Schönbeck , J C S 2020 , ' Cyclodextrin binding constants as a function of pH for compounds with multiple pKa values ' , International Journal of Pharmaceutics , vol. 585 , no. 585 , 119493 . https://doi.org/10.1016/j.ijpharm.2020.119493Test

مصطلحات موضوعية: Binding constant, Cyclodextrin, Drug development, Equilibrium, Graphical User Interface, Ionization, Monte Carlo simulation, Stability constants, pH

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016/j.ijpharm.2020.119493Test
https://forskning.ruc.dk/da/publications/ec5efb3c-a621-43aa-bf32-5ff8e428d2c4Test
https://hdl.handle.net/1800/ec5efb3c-a621-43aa-bf32-5ff8e428d2c4Test
https://rucforsk.ruc.dk/ws/files/68587892/Manuscript_2_.pdfTest

المؤلفون: Schönbeck, Jens Christian Sidney, Gaardahl, Karina, Houston, Bryan

المصدر: Schönbeck , J C S , Gaardahl , K & Houston , B 2019 , ' Drug Solubilization by Mixtures of Cyclodextrins : Additive and Synergistic Effects ' , Molecular Pharmaceutics , vol. 16 , no. 2 , pp. 648-654 . https://doi.org/10.1021/acs.molpharmaceut.8b00953Test

مصطلحات موضوعية: cyclodextrin, inclusion complex, phase-solubility, steroid

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1021/acs.molpharmaceut.8b00953Test
https://forskning.ruc.dk/da/publications/d9d4ef93-1aa1-45d2-8e62-ec671d6718d8Test
https://hdl.handle.net/1800/d9d4ef93-1aa1-45d2-8e62-ec671d6718d8Test
https://rucforsk.ruc.dk/ws/files/63984525/Sch_nbeck_et_al_2019_Drug_Solubilization_by_Mixtures_of_Cyclodextrins.pdfTest

المؤلفون: Schönbeck, Jens Christian Sidney, Madsen, Tobias Løvgren, Peters, Günther H., Holm, René, Loftsson, Thorsteinn

المصدر: Schönbeck , J C S , Madsen , T L , Peters , G H , Holm , R & Loftsson , T 2017 , ' Soluble 1:1 Complexes and Insoluble 3:2 Complexes : Understanding the Phase-Solubility Diagram of Hydrocortisone and γ-Cyclodextrin ' , International Journal of Pharmaceutics , vol. 531 , no. 2 , pp. 504-511 . https://doi.org/10.1016/j.ijpharm.2017.05.024Test

مصطلحات موضوعية: Binding constant, Calorimetry, Cyclodextrin, Hydrocortisone, Inclusion complex, Phase-solubility

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016/j.ijpharm.2017.05.024Test
https://forskning.ruc.dk/da/publications/f734894a-a6ec-4d67-a407-272d96abda93Test
https://hdl.handle.net/1800/f734894a-a6ec-4d67-a407-272d96abda93Test
https://rucforsk.ruc.dk/ws/files/59786918/Post_print.pdfTest
https://rucforsk.ruc.dk/ws/files/62824288/Supplementary_material_GammaCD_and_hydrocortisone.pdfTest

المؤلفون: Samuelsen, Lisa, Holm, René, Schönbeck, Jens Christian Sidney

المصدر: Samuelsen , L , Holm , R & Schönbeck , J C S 2021 , ' Specific Buffers Affect the Stability of a Charged Cyclodextrin Complex Via Competitive Binding and Ionic Strength ' , Journal of Pharmaceutical Sciences , vol. 110 , no. 7 , pp. 2661-2668 . https://doi.org/10.1016/j.xphs.2021.02.012Test

مصطلحات موضوعية: Complexation, Cyclodextrin(s), Equilibria, Formulation, Isothermal titration calorimetry (ITC)

الإتاحة: https://doi.org/10.1016/j.xphs.2021.02.012Test
https://forskning.ruc.dk/da/publications/8dc93ded-d3a5-46d7-87af-6800eb9b0d2fTest
https://hdl.handle.net/1800/8dc93ded-d3a5-46d7-87af-6800eb9b0d2fTest

المؤلفون: Olesen, Niels Erik, Westh, Peter, Holm, Rene

المصدر: Olesen , N E , Westh , P & Holm , R 2016 , ' Displacement of Drugs From Cyclodextrin Complexes by Bile Salts : A Suggestion of an Intestinal Drug-Solubilizing Capacity From an In Vitro Model ' , Journal of Pharmaceutical Sciences , vol. 105 , no. 9 , pp. 2640-2647 . https://doi.org/10.1002/jps.24678Test

مصطلحات موضوعية: mathematical model, solubilization, bile salts, cyclodextrin, calorimetry (ITC), complexation, micelle, intestinal absorption

الإتاحة: https://doi.org/10.1002/jps.24678Test
https://forskning.ruc.dk/da/publications/ec360565-6c43-4cc2-a51a-f44862b41f32Test
https://hdl.handle.net/1800/ec360565-6c43-4cc2-a51a-f44862b41f32Test

المؤلفون: Schönbeck, Jens Christian Sidney, Westh, Peter, Holm, René, Askjær, Sune

المصدر: Schönbeck , J C S , Westh , P , Holm , R & Askjær , S 2013 , ' Thermodynamics of the interaction of γ-cyclodextrin and tauro- and glyco-conjugated bile salts ' , Journal of Inclusion Phenomena and Macrocyclic Chemistry , vol. 75 , no. 1-2 , pp. 223-233 . https://doi.org/10.1007/s10847-012-0165-1Test

مصطلحات موضوعية: Isothermal titration calorimetry, Bile salts, Complexation, Cyclodextrin, Gamma-cyclodextrin, Molecular modelling

الإتاحة: https://doi.org/10.1007/s10847-012-0165-1Test
https://forskning.ruc.dk/da/publications/37694bd4-d8e2-471e-ac80-860cbd4f168dTest
https://hdl.handle.net/1800/37694bd4-d8e2-471e-ac80-860cbd4f168dTest

المؤلفون: Holm, Rene, Schönbeck, Jens Christian Sidney, Askjær, Sune, Jensen, Henrik, Westh, Peter, Østergaard, Jesper

المصدر: Holm , R , Schönbeck , J C S , Askjær , S , Jensen , H , Westh , P & Østergaard , J 2011 , ' Complexation of tauro- and glyco-conjugated bile salts with alpha-cyclodextrin and hydroxypropyl-alpha-cyclodextrin studied by affinity capillary electrophoresis and molecular modelling ' , Journal of Separation Science , vol. 34 , no. 22 , pp. 3221-3230 . https://doi.org/10.1002/jssc.201100479Test

مصطلحات موضوعية: alpha-Cyclodextrin, Bile salts, Biological surfactants, Complexationi, Structure analysis

الإتاحة: https://doi.org/10.1002/jssc.201100479Test
https://forskning.ruc.dk/da/publications/4919a0fd-b35a-4801-bbd1-6d7edabda579Test
https://hdl.handle.net/1800/4919a0fd-b35a-4801-bbd1-6d7edabda579Test