دورية أكاديمية
Detection of prefrontal lobe blood flow changes in patients with obsessivecompulsive disorder during a verbal fluency task by near-infrared reflectance spectroscopy. / Detección de cambios en el flujo sanguíneo del lóbulo prefrontal en pacientes con trastorno obsesivo-compulsivo, durante una tarea de fluidez verbal, mediante espectroscopia de reflectancia en el infrarrojo cercano.
| العنوان: | Detection of prefrontal lobe blood flow changes in patients with obsessivecompulsive disorder during a verbal fluency task by near-infrared reflectance spectroscopy. / Detección de cambios en el flujo sanguíneo del lóbulo prefrontal en pacientes con trastorno obsesivo-compulsivo, durante una tarea de fluidez verbal, mediante espectroscopia de reflectancia en el infrarrojo cercano. |
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| المؤلفون: | Yin, Hong-Ying, Jiang, Fan, Peng, Qi-Hua, Wu, Yu-Ling |
| المصدر: | Investigación Clínica; Vol. 61 Núm. 2 (2020): Investigación Clínica; 132-141 ; 2477-9393 ; 0535-5133 |
| بيانات النشر: | Universidad del Zulia |
| سنة النشر: | 2020 |
| المجموعة: | RevicyhLUZ - Revistas Científicas y Humanísticas de la Universidad del Zulia |
| مصطلحات موضوعية: | near-infrared reflectance spectroscopy, obsessive-compulsive disorder, verbal fluency, oxygenate hemoglobin, deoxygenate hemoglobin, espectroscopía de reflectancia casi infrarroja, trastorno obsesivo compulsivo, fluidez verbal, hemoglobina oxigenada |
| الوصف: | The purpose of this work was to use near-infrared reflectance spectroscopy (NIRS) to investigate the spectral characteristics and frontal lobe activation in patients with obsessive-compulsive disorder (OCD) during a verbal fluency task. Thirty-seven patients with OCD, who met the diagnostic criteria of International Classification of Diseases 10 (ICD-10), were recruited. The total score of the Symptom Checklist (SCL-90, grade 1-5) was ≥160 points. The total score of the Yale-Brown Obsessive Compulsive Scale was ≥7 points. The changes in frontal lobe blood flow were measured by NIRS when completing a verbal fluency task. Then, the differences between obsessive-compulsive thoughts and obsessive-compulsive behaviors in OCD, and the concentration variation of oxygenate hemoglobin (Oxy-Hb) and deoxygenate hemoglobin (Deoxy-Hb) were investigated. The difference was significant (P<0.03) between obsessive-compulsive behaviors and obsessive-compulsive thoughts. Obsessive-compulsive behaviors were positively correlated (P<0.01, P<0.05) with depression, anxiety, psychosis and other factors in the SCL-90, and significantly positively correlated (P<0.01, P<0.03) with somatization, hostility and paranoid factor scores in the SCL-90. There was also a trend of partial overlap between the waveform and task period, and the difference was significant (P<0.01) between these. Obsessive-compulsive thoughts were negatively correlated (P<0.05) with channels 9 and 19. The NIRS monitoring spectrum for patients with OCD has certain spectral characteristics of schizophrenia, but there is a repetitive trend between the recovery period and the task period.Resumen.El propósito del presente trabajo fue utilizar la espectroscopia de reflectancia en el infrarrojo cercano (NIRS) para investigar las características espectrales y la activación del lóbulo frontal en el trastorno obsesivo compulsivo (TOC) durante una tarea de fluidez verbal. Se reclutaron 37 pacientes con TOC que cumplían los criterios de diagnóstico de ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf; text/html |
| اللغة: | Spanish; Castilian |
| العلاقة: | https://www.produccioncientificaluz.org/index.php/investigacion/article/view/32914/34475Test; https://www.produccioncientificaluz.org/index.php/investigacion/article/view/32914/htmlTest; https://www.produccioncientificaluz.org/index.php/investigacion/article/view/32914Test |
| DOI: | 10.22209/IC.v61n2a04 |
| الإتاحة: | https://doi.org/10.22209/IC.v61n2a04Test https://www.produccioncientificaluz.org/index.php/investigacion/article/view/32914Test |
| حقوق: | Derechos de autor 2020 Investigación Clínica |
| رقم الانضمام: | edsbas.4AEF16BF |
| قاعدة البيانات: | BASE |
| DOI: | 10.22209/IC.v61n2a04 |
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