التفاصيل البيبلوغرافية
| العنوان: |
NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis |
| المؤلفون: |
Singer, Jochen, Ruscheweyh, Hans-Joachim, Hofmann, Ariane L., Thurnherr, Thomas, Singer, Franziska, Toussaint, Nora C., Ng, Charlotte K Y., Piscuoglio, Salvatore, Beisel, Christian, Christofori, Gerhard, Dummer, Reinhard, Hall, Michael N., Krek, Wilhelm, Levesque, Mitchell P., Manz, Markus G., Moch, Holger, Papassotiropoulos, Andreas, Stekhoven, Daniel J., Wild, Peter, Wüst, Thomas, Rinn, Bernd, Beerenwinkel, Niko, Berger, Bonnie |
| سنة النشر: |
2021 |
| المجموعة: |
réro doc Digital Library (Library Network of Western Switzerland / Réseau des bibliothèques de Suisse occidentale) |
| الوصف: |
Motivation Next-generation sequencing is now an established method in genomics, and massive amounts of sequencing data are being generated on a regular basis. Analysis of the sequencing data is typically performed by lab-specific in-house solutions, but the agreement of results from different facilities is often small. General standards for quality control, reproducibility and documentation are missing. Results We developed NGS-pipe, a flexible, transparent and easy-to-use framework for the design of pipelines to analyze whole-exome, whole-genome and transcriptome sequencing data. NGS-pipe facilitates the harmonization of genomic data analysis by supporting quality control, documentation, reproducibility, parallelization and easy adaptation to other NGS experiments. Availability and implementation https://github.com/cbg-ethz/NGS-pipeTest |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
English |
| العلاقة: |
http://doc.rero.ch/record/332504/files/BIOINFORMATICS_34_1_107.pdfTest |
| الإتاحة: |
http://doc.rero.ch/record/332504/files/BIOINFORMATICS_34_1_107.pdfTest |
| رقم الانضمام: |
edsbas.190D37BF |
| قاعدة البيانات: |
BASE |
