رسالة جامعية
Developing Adaptive and Predictive Modules for the Second Generation of Multivariable Insulin Delivery System for People with Type-1 Diabetes
| العنوان: | Developing Adaptive and Predictive Modules for the Second Generation of Multivariable Insulin Delivery System for People with Type-1 Diabetes |
|---|---|
| المؤلفون: | Askari, Mohammad Reza |
| المساهمون: | Cinar, Ali |
| المصدر: | Illinois Institute of Technology ; ChBE / Chemical and Biological Engineering |
| سنة النشر: | 2023 |
| المجموعة: | repository.iit (Illinois Institute of Technology) |
| مصطلحات موضوعية: | Engineering, Artificial Pancreas, Insulin Delivery System, Type-1 Diabetes |
| الوصف: | In this research, we are developing the second generation of multivariable automated insulin delivery system (mvAID) for people with Type 1 diabetes (T1D). AID system is improved by integrating missing data from sensors into the system, reconciling outliers in the data, and eliminating the effects of artifacts in signals from wearable devices. Behavioral patterns of individuals with T1D are captured by data-driven models. The model predictive control algorithm of the mvAID uses these patterns for making decisions and predicting glucose concentrations in the future more accurately. A pipeline algorithm is developed for removing noise and motion artifacts from wristband signals. Then, energy expenditure, physical activity, and acute psychological stress (APS) are estimated from wearable device signals to detect and quantify disturbances affecting the concentration of blood glucose concentration. Additionally, different modules were designed for predicting risky glycemic episodes and are used to build the second generation of the mvAID system. The techniques developed are tested with historical data sets from various clinical experiments and free-living data, and with simulations made by using our multivariable glucose, insulin and physiological variables simulator (mGIPsim). |
| نوع الوثيقة: | doctoral or postdoctoral thesis |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | islandora:1024314; http://hdl.handle.net/10560/islandora:1024314Test; http://repository.iit.edu/islandora/object/islandora%3A1024314/datastream/TN/view/Developing%20Adaptive%20and%20Predictive%20Modules%20for%20the%20Second%20Generation%20of%20Multivariable%20Insulin%20Delivery%20System%20for%20People%20with%20Type-1%20Diabetes.jpgTest |
| الإتاحة: | http://hdl.handle.net/10560/islandora:1024314Test http://repository.iit.edu/islandora/object/islandora%3A1024314/datastream/TN/view/Developing%20Adaptive%20and%20Predictive%20Modules%20for%20the%20Second%20Generation%20of%20Multivariable%20Insulin%20Delivery%20System%20for%20People%20with%20Type-1%20Diabetes.jpgTest |
| حقوق: | In Copyright ; http://rightsstatements.org/page/InC/1.0Test/ ; Restricted Access |
| رقم الانضمام: | edsbas.EE002E86 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |