دورية أكاديمية
Effects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apnea
العنوان: | Effects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apnea |
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المؤلفون: | Feliciano, A., Oliveira, M.J., Cysneiros, A., Martinho, C., Reis, R.P., Penque, D., Pinto, P., Bárbara, C. |
المساهمون: | NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) |
سنة النشر: | 2017 |
المجموعة: | Repositório da Universidade Nova de Lisboa (UNL) |
مصطلحات موضوعية: | Glucose metabolism, HOMA-IR, Homocysteine, Lipid metabolism, Obstructive sleep apnea, PAP |
الوصف: | Introduction Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular/metabolic complications. Some analytical parameters (homocysteine, glycemic and lipidic profiles) are recognized markers of these consequences. Limited data is available on the association of these markers and OSAS's severity/response to positive airway pressure therapy (PAP). Material and methods In this prospective study we analyzed polysomnographic and analytical data of male patients admitted to sleep laboratory. The aim was to evaluate metabolic/cardiovascular markers in snorers and OSAS patients, to relate with sleep parameters and PAP response. One-hundred and three patients were included, and 73 (71%) were OSAS patients. OSAS patients were similar to snorers except for higher body mass index (BMI) and dyslipidemia. Severe OSAS patients showed higher glycemia, HbA1c, insulin, and insulin resistance, and lower HDL cholesterol in comparison to mild–moderate (p ; publishersversion ; published |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 2173-5115 |
العلاقة: | PURE: 3229020; PURE UUID: b82106b0-1375-4667-a5ea-3875ab1f3111; RIS: urn:99D700E4558A13E8CC576729993520A2; Scopus: 85020993055; PubMed: 28596012; WOS: 000405642500004; http://hdl.handle.net/10362/147884Test; https://doi.org/10.1016/j.rppnen.2017.02.010Test |
DOI: | 10.1016/j.rppnen.2017.02.010 |
الإتاحة: | https://doi.org/10.1016/j.rppnen.2017.02.010Test http://hdl.handle.net/10362/147884Test |
حقوق: | openAccess |
رقم الانضمام: | edsbas.FD22D3E0 |
قاعدة البيانات: | BASE |
تدمد: | 21735115 |
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DOI: | 10.1016/j.rppnen.2017.02.010 |