دورية أكاديمية

Effects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apnea

التفاصيل البيبلوغرافية
العنوان: Effects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apnea
المؤلفون: Feliciano, A., Oliveira, M.J., Cysneiros, A., Martinho, C., Reis, R.P., Penque, D., Pinto, P., Bárbara, C.
المساهمون: NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
سنة النشر: 2017
المجموعة: Repositório da Universidade Nova de Lisboa (UNL)
مصطلحات موضوعية: Glucose metabolism, HOMA-IR, Homocysteine, Lipid metabolism, Obstructive sleep apnea, PAP
الوصف: Introduction Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular/metabolic complications. Some analytical parameters (homocysteine, glycemic and lipidic profiles) are recognized markers of these consequences. Limited data is available on the association of these markers and OSAS's severity/response to positive airway pressure therapy (PAP). Material and methods In this prospective study we analyzed polysomnographic and analytical data of male patients admitted to sleep laboratory. The aim was to evaluate metabolic/cardiovascular markers in snorers and OSAS patients, to relate with sleep parameters and PAP response. One-hundred and three patients were included, and 73 (71%) were OSAS patients. OSAS patients were similar to snorers except for higher body mass index (BMI) and dyslipidemia. Severe OSAS patients showed higher glycemia, HbA1c, insulin, and insulin resistance, and lower HDL cholesterol in comparison to mild–moderate (p ; publishersversion ; published
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 2173-5115
العلاقة: PURE: 3229020; PURE UUID: b82106b0-1375-4667-a5ea-3875ab1f3111; RIS: urn:99D700E4558A13E8CC576729993520A2; Scopus: 85020993055; PubMed: 28596012; WOS: 000405642500004; http://hdl.handle.net/10362/147884Test; https://doi.org/10.1016/j.rppnen.2017.02.010Test
DOI: 10.1016/j.rppnen.2017.02.010
الإتاحة: https://doi.org/10.1016/j.rppnen.2017.02.010Test
http://hdl.handle.net/10362/147884Test
حقوق: openAccess
رقم الانضمام: edsbas.FD22D3E0
قاعدة البيانات: BASE
الوصف
تدمد:21735115
DOI:10.1016/j.rppnen.2017.02.010