مراجعة
Leveraging the future of diagnosis and management of diabetes ; From old indexes to new technologies
| العنوان: | Leveraging the future of diagnosis and management of diabetes ; From old indexes to new technologies |
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| المؤلفون: | Meneses, Maria João, Patarrão, Rita Susana, Pinheiro, Tomás, Coelho, Inês, Carriço, Nuno, Marques, Ana Carolina, Romão, Artur, Nabais, João, Fortunato, Elvira, Raposo, João Filipe, Macedo, Maria Paula |
| المساهمون: | NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), iNOVA4Health - pólo NMS, CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N), DCM - Departamento de Ciência dos Materiais, Faculdade de Ciências e Tecnologia (FCT), UNINOVA-Instituto de Desenvolvimento de Novas Tecnologias |
| سنة النشر: | 2023 |
| المجموعة: | Repositório da Universidade Nova de Lisboa (UNL) |
| مصطلحات موضوعية: | C-peptide, glycemic variability, HbA1c, indexes, insulin resistance, insulin sensitivity, oral glucose tolerance test, prediabetes, type 2 diabetes, Biochemistry, Clinical Biochemistry, SDG 3 - Good Health and Well-being |
| الوصف: | Funding Information: This work was supported by FEDER, Portugal2020, and co‐financed by Lisboa2020 and Alentejo2020 (ALT20‐03‐0247‐FEDER‐113469 and LISBOA‐01‐0247‐FEDER‐113469), ‘Fundação para a Ciência e a Tecnologia’—FCT iNOVA4Health (UIDB/Multi/04462/2020), European Commission Marie Skłodowska‐Curie Action H2020 (mtFOIE GRAS, grant agreement n. 734719) and the Sociedade Portuguesa de Diabetologia. Publisher Copyright: © 2022 The Authors. European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation. ; Background: Diabetes is a heterogeneous and multifactorial disease. However, glycemia and glycated hemoglobin have been the focus of diabetes diagnosis and management for the last decades. As diabetes management goes far beyond glucose control, it has become clear that assessment of other biochemical parameters gives a much wider view of the metabolic state of each individual, enabling a precision medicine approach. Methods: In this review, we summarize and discuss indexes that have been used in epidemiological studies and in the clinical practice. Results: Indexes of insulin secretion, sensitivity/resistance and metabolism have been developed and validated over the years to account also with insulin, C-peptide, triglycerides or even anthropometric measures. Nevertheless, each one has their own objective and consequently, advantages and disadvantages for specific cases. Thus, we discuss how new technologies, namely new sensors but also new softwares/applications, can improve the diagnosis and management of diabetes, both for healthcare professionals but also for caretakers and, importantly, to promote the empowerment of people living with diabetes. Conclusions: In long-term, the solution for a better diabetes management would be a platform that allows to integrate all sorts of relevant information for the person with diabetes and for the healthcare practitioners, namely glucose, insulin and C-peptide or, in ... |
| نوع الوثيقة: | review |
| اللغة: | English |
| ردمك: | 978-85-14-49908-4 978-0-00-901593-9 85-14-49908-4 0-00-901593-0 |
| تدمد: | 0014-2972 |
| العلاقة: | PURE: 49700267; PURE UUID: ad3e219a-76bd-466b-ac87-35f326924831; Scopus: 85144990843; PubMed: 36479853; WOS: 000901593000001; http://hdl.handle.net/10362/147244Test; https://doi.org/10.1111/eci.13934Test |
| DOI: | 10.1111/eci.13934 |
| الإتاحة: | https://doi.org/10.1111/eci.13934Test http://hdl.handle.net/10362/147244Test |
| حقوق: | openAccess |
| رقم الانضمام: | edsbas.5C00193A |
| قاعدة البيانات: | BASE |
| ردمك: | 9788514499084 9780009015939 8514499084 0009015930 |
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| تدمد: | 00142972 |
| DOI: | 10.1111/eci.13934 |