دورية أكاديمية
Smoking and survival in male breast cancer patients.
| العنوان: | Smoking and survival in male breast cancer patients. |
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| المؤلفون: | Padron-Monedero, Alicia, Koru-Sengul, Tulay, Tannenbaum, Stacey L, Miao, Feng, Hansra, Damien, Lee, David J, Byrne, Margaret M |
| المساهمون: | James & Esther King Florida Biomedical Research Program |
| بيانات النشر: | Springer |
| سنة النشر: | 2015 |
| المجموعة: | REPISALUD (REPositorio Institucional en SALUD del Instituto de Salud Carlos III - ISCIII) |
| مصطلحات موضوعية: | Health inequalities, Male breast cancer, Smoking, Survival, Adult, Aged, 80 and over, Breast Neoplasms, Male, Comorbidity, Florida, Humans, Middle Aged, Models, Statistical, Mortality, Population Surveillance, Registries, Socioeconomic Factors |
| الوصف: | The purpose of the article was to assess whether smoking affects survival in male breast cancer patients for the overall population and when stratified by race, ethnicity, and socioeconomic status. Data were obtained by linking the 1996-2007 Florida Cancer Data System, the Florida Agency for Health Care Administration, and the US Census. Inclusion criteria were males ≥18 years, diagnosed with breast cancer and residing in Florida (n = 1573). To analyze the association between smoking and survival, we performed sequential multivariate Cox proportional hazards regression models with progressive adjustment for main confounders. Compared to never smokers, worse survival was found in current (hazard ratio = 1.63; 95 % CI = 1.23-2.16) but not in former smokers (1.26; 0.99-1.59). Those who smoked ≥1 packs/day had worse survival (2.48; 1.59-3.87) than never smokers with a significant dose-response (P for linear trend <0.001). Race-ethnic stratified models comparing current and former smokers with never smokers found significant differences among Whites [(1.88; 1.44-2.44) and (1.31; 1.04-1.65, respectively)] and non-Hispanics, [(1.73; 1.31-2.28) and (1.31; 1.04-1.66, respectively)]. Overall, current smokers were found to have significantly reduced survival, which was worse by intensity of smoking. Also, any smoking history is associated with worse survival in White and non-Hispanic male breast cancer patients compared to never smokers. Thus, male breast cancer patients should be advised to quit smoking. ; This study was funded by the James & Esther King Florida Biomedical Research Program (Grant 10KG-06). ; Sí |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1573-7217 |
| العلاقة: | Postprint; https://doi.org/10.1007/s10549-015-3582-1Test; Breast Cancer Res Treat . 2015 Oct;153(3):679-87; http://hdl.handle.net/20.500.12105/11656Test; Breast cancer research and treatment |
| DOI: | 10.1007/s10549-015-3582-1 |
| الإتاحة: | https://doi.org/20.500.12105/11656Test https://doi.org/10.1007/s10549-015-3582-1Test https://hdl.handle.net/20.500.12105/11656Test |
| حقوق: | http://creativecommons.org/licenses/by-nc-sa/4.0Test/ ; Atribución-NoComercial-CompartirIgual 4.0 Internacional ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.2D02854E |
| قاعدة البيانات: | BASE |
| تدمد: | 15737217 |
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| DOI: | 10.1007/s10549-015-3582-1 |