دورية أكاديمية
Organochlorinated pesticides levels in a representative sample of the Spanish adult population: The Bioambient.es project
| العنوان: | Organochlorinated pesticides levels in a representative sample of the Spanish adult population: The Bioambient.es project |
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| المؤلفون: | Ramos, Juan Jose, Huetos, Olga, Gonzalez-Hernández, Sara, Esteban-Lopez, Marta, Calvo, Eva, Perez-Gomez, Beatriz, Castaño, Argelia |
| المساهمون: | Instituto de Salud Carlos III |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2017 |
| المجموعة: | REPISALUD (REPositorio Institucional en SALUD del Instituto de Salud Carlos III - ISCIII) |
| مصطلحات موضوعية: | Biomarkers, Blood serum, DDE, DDT, Human biomonitoring, Organochlorinated pesticides, Spain, β-HCH, Adult, Environmental Monitoring, Environmental Pollutants, Female, Humans, Hydrocarbons, Chlorinated, Male, Middle Aged, Pesticides, Reference Values |
| الوصف: | Organochlorinated pesticides (OCPs) were measured in a representative sample of Spanish adults within the Bioambient.es project, a nationwide human biomonitoring program promoted by Spanish Ministry of Agriculture, Food and Environment. The objective of Bioambient.es is to establish reference levels of environmental pollutants in the general population. Participants were recruited in 2009-2010 during their annual medical examination at work. Serum levels of thirteen OCPs were investigated: Aldrin, endrin, dieldrin, heptachlor, heptachlor-epoxide, dichlorodiphenyldichloroethylenes (DDEs), hexachlorobenzene (HCB), dichlorodiphenyltrichloroethanes (DDTs) and hexachlorocyclohexanes (HCHs) The highest concentrations were observed for DDE, HCB and β-HCH. The 95th percentile, in ng/g lipids, were: 717.7 for 4,4-DDE, 160.4 for HCB and 107.2 for β-HCH, while concentrations of aldrin, endrin, heptachlor, α-HCH, 2,4-DDT, 4,4-DDT and 2,4-DDE were markedly lower and detected in less than 10% of the samples. Significant differences (p<0.05) were found for DDE and HCB and seasonality, gender and age. Analyzing the geographical distribution, participants from the north of Spain had highest levels of HCB while those from the center of Spain had highest levels of 4,4-DDE. Comparing to earlier studies, the results indicated a sharp decline in the OCP concentrations in the Spanish population over time, and today values are in the same range or lower than those reported in similar studies worldwide, except for HCHs and HCB that presented higher levels than in other European countries and much higher than those observed in US and Canada. This study represents the first nationwide survey of exposure to OCPs in Spain and provides a background reference range for exposure to OCPs in the Spanish adult occupied population. These results will allow establishing reference values, observing temporal trends and identifying high exposure groups. ; Funded by the research agreement between the Spanish Ministry of Agriculture, Food and the ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1438-4639 1618-131X |
| العلاقة: | https://doi.org/10.1016/j.ijheh.2016.10.005Test; Int J Hyg Environ Health. 2017 Mar;220(2 Pt A):217-226.; http://hdl.handle.net/20.500.12105/10232Test; International journal of hygiene and environmental health |
| DOI: | 10.1016/j.ijheh.2016.10.005 |
| الإتاحة: | https://doi.org/20.500.12105/10232Test https://doi.org/10.1016/j.ijheh.2016.10.005Test https://hdl.handle.net/20.500.12105/10232Test |
| حقوق: | http://creativecommons.org/licenses/by-nc-sa/4.0Test/ ; Atribución-NoComercial-CompartirIgual 4.0 Internacional ; open access |
| رقم الانضمام: | edsbas.C3802968 |
| قاعدة البيانات: | BASE |
| تدمد: | 14384639 1618131X |
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| DOI: | 10.1016/j.ijheh.2016.10.005 |