دورية أكاديمية
The dynamic changes of dominant clones of Staphylococcus aureus causing bloodstream infections in the European region: results of a second structured survey
| العنوان: | The dynamic changes of dominant clones of Staphylococcus aureus causing bloodstream infections in the European region: results of a second structured survey |
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| المؤلفون: | Grundmann, H, Schouls, L M, Aanensen, D M, Pluister, G N, Tami, A, Chlebowicz, M, Glasner, C, Sabat, A J, Weist, K, Heuer, O, Friedrich, A W, ESCMID Study Group on Molecular Epidemiological Markers, European Staphylococcal Reference Laboratory Working Group, Perez-Vazquez, Maria |
| المساهمون: | Unión Europea. European Centre for Disease Prevention and Control (ECDC) |
| بيانات النشر: | European Centre for Disease Prevention and Control (ECDC) |
| سنة النشر: | 2014 |
| المجموعة: | REPISALUD (REPositorio Institucional en SALUD del Instituto de Salud Carlos III - ISCIII) |
| مصطلحات موضوعية: | Anti-Bacterial Agents, Bacterial Typing Techniques, Data Collection, Europe, Female, Genetic Variation, Genotype, Humans, Male, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Molecular Epidemiology, Multilocus Sequence Typing, Staphylococcal Infections, Staphylococcal Protein A, Staphylococcus aureus |
| الوصف: | Staphylococcus aureus is one of the most important human pathogens and meticillin-resistant S. aureus (MRSA) presents a major cause of healthcare- and community-acquired infections. This study investigated the spatial and temporal changes of S. aureus causing bacteraemia in Europe over a five-year interval and explored the possibility of integrating pathogen-based typing data with epidemiological and clinical information at a European level. Between January 2011 and July 2011, 350 laboratories serving 453 hospitals in 25 countries collected 3,753 isolates (meticillin-sensitive S. aureus (MSSA) and MRSA) from patients with S. aureus bloodstream infections. All isolates were sent to the national staphylococcal reference laboratories and characterised by quality-controlled spa typing. Data were uploaded to an interactive web-based mapping tool. A wide geographical distribution of spa types was found, with some prevalent in all European countries. MSSA was more diverse than MRSA. MRSA differed considerably between countries with major international clones expanding or receding when compared to a 2006 survey. We provide evidence that a network approach of decentralised typing and visualisation of aggregated data using an interactive mapping tool can provide important information on the dynamics of S. aureus populations such as early signalling of emerging strains, cross-border spread and importation by travel. ; The study was funded by ECDC through tender and frame-work contract ECDC 09/033. ; Sí |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1560-7917 |
| العلاقة: | https://doi.org/10.2807/1560-7917.es2014.19.49.20987Test; Euro Surveill. 2014 Dec 11;19(49):20987.; http://hdl.handle.net/20.500.12105/16129Test; Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin |
| DOI: | 10.2807/1560-7917.es2014.19.49.20987 |
| الإتاحة: | https://doi.org/20.500.12105/16129Test https://doi.org/10.2807/1560-7917.es2014.19.49.20987Test https://hdl.handle.net/20.500.12105/16129Test |
| حقوق: | http://creativecommons.org/licenses/by/4.0Test/ ; Atribución 4.0 Internacional ; open access |
| رقم الانضمام: | edsbas.6A642024 |
| قاعدة البيانات: | BASE |
| تدمد: | 15607917 |
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| DOI: | 10.2807/1560-7917.es2014.19.49.20987 |