دورية أكاديمية
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium.
العنوان: | Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium. |
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المؤلفون: | Koivula, R. W., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A. D., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M. W., Perry, Mandy, Rauh, S., Siloaho, M., Teare, H. J. A., Thorand, B., Bell, J., Brunak, S., Frost, G., Jablonka, B., Mari, A., McDonald, Timothy J., Dekker, J. M., Hansen, T. V. O., Hattersley, Andrew T., Laakso, M., Pedersen, O., Koivisto, V., Ruetten, H., Walker, M., Pearson, E. R., Franks, P. W. |
بيانات النشر: | Springer |
سنة النشر: | 2016 |
المجموعة: | RD&E Research Repository (Royal Devon and Exeter NHS Foundation Trust) |
مصطلحات موضوعية: | Wessex Classification Subject Headings::Oncology. Pathology.::Genetics, Wessex Classification Subject Headings::Endocrinology::Diabetes |
الوصف: | The DIRECT (Diabetes Research on Patient Stratification) Study is part of a European Union Framework 7 Innovative Medicines Initiative project, a joint undertaking between four industry and 21 academic partners throughout Europe. The Consortium aims to discover and validate biomarkers that: (1) predict the rate of glycaemic deterioration before and after type 2 diabetes onset; (2) predict the response to diabetes therapies; and (3) help stratify type 2 diabetes into clearly definable disease subclasses that can be treated more effectively than without stratification. This paper describes two new prospective cohort studies conducted as part of DIRECT. ; This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text via the publisher's site. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 1432-0428 |
العلاقة: | http://dx.doi.org/10.1007/s00125-014-3216-xTest; Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium. 2014, 57 (6):1132-42 Diabetologia; http://hdl.handle.net/11287/618023Test; Diabetologia |
DOI: | 10.1007/s00125-014-3216-x |
الإتاحة: | https://doi.org/10.1007/s00125-014-3216-xTest http://hdl.handle.net/11287/618023Test |
حقوق: | Archived with thanks to Diabetologia |
رقم الانضمام: | edsbas.2A5A7D47 |
قاعدة البيانات: | BASE |
تدمد: | 14320428 |
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DOI: | 10.1007/s00125-014-3216-x |