دورية أكاديمية
Unraveling the clinicopathological and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-low and HER2-0 breast cancer.
| العنوان: | Unraveling the clinicopathological and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-low and HER2-0 breast cancer. |
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| المؤلفون: | Schettini, F, Nucera, S, Brasó-Maristany, F, De Santo, I, Pascual, T, Bergamino, M, Galván, P, Conte, B, Seguí, E, García Fructuoso, I, Gómez Bravo, R, Rivera, P, Rodríguez, A B, Martínez-Sáez, O, Ganau, S, Sanfeliu, E, González-Farre, B, Vidal Losada, M J, Adamo, B, Cebrecos, I, Mension, E, Oses, G, Jares, P, Vidal-Sicart, S, Mollà, M, Muñoz, M, Prat, A |
| المصدر: | ESMO Open ; ISSN:2059-7029 ; Volume:9 ; Issue:7 |
| بيانات النشر: | Elsevier Science |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | HER2 dynamics, HER2-low, hormone receptor-positive, neoadjuvant chemotherapy, neoadjuvant endocrine therapy |
| الوصف: | The characterization and comparison of gene expression and intrinsic subtype (IS) changes induced by neoadjuvant chemotherapy (NACT) and endocrine therapy in hormone receptor-positive (HR+)/human epidermal growth factor receptor 2 (HER2)-low versus HR+/HER2-0 breast cancer (BC) has not been conducted so far. Most evidence on the association of HER2 status with pathologic responses and prognosis in HR+/HER2-negative BC is controversial and restricted to NACT-treated disease. Similarly, a temporal heterogeneity in HER2 status has been described only with NACT. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.1016/j.esmoop.2024.103619Test; https://pubmed.ncbi.nlm.nih.gov/38943737Test |
| DOI: | 10.1016/j.esmoop.2024.103619 |
| الإتاحة: | https://doi.org/10.1016/j.esmoop.2024.103619Test https://pubmed.ncbi.nlm.nih.gov/38943737Test |
| حقوق: | Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved. |
| رقم الانضمام: | edsbas.8C4DAC83 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.esmoop.2024.103619 |
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