دورية أكاديمية
Artifactually increased serum bicarbonate in a cat with rhabdomyolysis.
| العنوان: | Artifactually increased serum bicarbonate in a cat with rhabdomyolysis. |
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| المؤلفون: | Wynter, Zoe R, Ruane, Emily, Kortum, Andre J, Hare, Cassia H Z |
| المصدر: | Vet Clin Pathol ; ISSN:1939-165X |
| بيانات النشر: | Wiley |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | feline, lactate dehydrogenase, muscle, pyruvate |
| الوصف: | A 3-year-old male neutered domestic shorthair cat presented with lethargy, hyporexia, and pyrexia of unknown origin. Biochemical analysis using a Beckman Coulter AU480 demonstrated marked increases in creatine kinase and aspartate aminotransferase, indicative of severe muscle injury, with concurrent presumptive myoglobinuria on urinalysis. A marked, non-physiologic increase in measured bicarbonate and resultant negative anion gap was documented; however, calculated bicarbonate obtained via a point-of-care blood gas analyzer was within normal limits. Laboratory error due to interference by lactate dehydrogenase was suspected and supported by the results of subsequent biochemical testing. Artifactual increases in bicarbonate have been documented in cases of rhabdomyolysis in horses, cows, and a bird. However, to the best of the authors' knowledge, this is the first report to demonstrate this spurious change in a cat. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.1111/vcp.13371Test; https://pubmed.ncbi.nlm.nih.gov/38872478Test |
| DOI: | 10.1111/vcp.13371 |
| الإتاحة: | https://doi.org/10.1111/vcp.13371Test https://pubmed.ncbi.nlm.nih.gov/38872478Test |
| حقوق: | © 2024 The Author(s). Veterinary Clinical Pathology published by Wiley Periodicals LLC on behalf of American Society for Veterinary Clinical Pathology. |
| رقم الانضمام: | edsbas.4E98045F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/vcp.13371 |
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