دورية أكاديمية
Colorectal carcinoma peritoneal metastases-derived organoids: results and perspective of a model for tailoring hyperthermic intraperitoneal chemotherapy from bench-to-bedside.
| العنوان: | Colorectal carcinoma peritoneal metastases-derived organoids: results and perspective of a model for tailoring hyperthermic intraperitoneal chemotherapy from bench-to-bedside. |
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| المؤلفون: | Varinelli, Luca, Battistessa, Davide, Guaglio, Marcello, Zanutto, Susanna, Illescas, Oscar, Lorenc, Ewelina J, Pisati, Federica, Kusamura, Shigeki, Cattaneo, Laura, Sabella, Giovanna, Milione, Massimo, Perbellini, Alessia, Noci, Sara, Paolino, Cinzia, Kuhn, Elisabetta, Galassi, Margherita, Cavalleri, Tommaso, Deraco, Marcello, Gariboldi, Manuela, Baratti, Dario |
| المصدر: | J Exp Clin Cancer Res ; ISSN:1756-9966 ; Volume:43 ; Issue:1 |
| بيانات النشر: | BioMed Central |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | Chemotherapy, Colorectal cancer, HIPEC, Organoids, Peritoneal metastases, Personalized medicine, Tailored therapies |
| الوصف: | Peritoneal metastases from colorectal cancer (CRCPM) are related to poor prognosis. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have been reported to improve survival, but peritoneal recurrence rates are still high and there is no consensus on the drug of choice for HIPEC. The aim of this study was to use patient derived organoids (PDO) to build a relevant CRCPM model to improve HIPEC efficacy in a comprehensive bench-to-bedside strategy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.1186/s13046-024-03052-5Test; https://pubmed.ncbi.nlm.nih.gov/38698446Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11064374Test/ |
| DOI: | 10.1186/s13046-024-03052-5 |
| الإتاحة: | https://doi.org/10.1186/s13046-024-03052-5Test https://pubmed.ncbi.nlm.nih.gov/38698446Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11064374Test/ |
| حقوق: | © 2024. The Author(s). |
| رقم الانضمام: | edsbas.688A45EE |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13046-024-03052-5 |
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