دورية أكاديمية
Evaluation of a new body-focused group therapy versus a guided self-help group program for adults with psychogenic non-epileptic seizures (PNES): a pilot randomized controlled feasibility study
| العنوان: | Evaluation of a new body-focused group therapy versus a guided self-help group program for adults with psychogenic non-epileptic seizures (PNES): a pilot randomized controlled feasibility study |
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| المؤلفون: | Senf-Beckenbach, Philine, Hoheisel, Matthias, Devine, Janine, Frank, Arnina, Obermann, Laura, Rose, Matthias, Hinkelmann, Kim |
| المصدر: | http://lobid.org/resources/99370671259506441Test#!, 269(1):427-436. |
| سنة النشر: | 2021 |
| المجموعة: | Publisso (ZB MED-Publikationsportal Lebenswissenschaften) |
| مصطلحات موضوعية: | Psychotherapy, Group [MeSH], Randomized clinical feasibility study, Adult [MeSH], Seizures/therapy [MeSH], Humans [MeSH], Self-Help Groups [MeSH], Electroencephalography [MeSH], Feasibility Studies [MeSH], Group psychotherapy treatment, Psychogenic non-epileptic seizures, Pilot Projects [MeSH], Body psychotherapy, Dissociative seizures, Original Communication |
| الوصف: | Objective!#!Psychogenic non-epileptic seizures (PNES), a common phenomenon in neurological settings, are regarded as a paroxysmal type of functional neurological disorder (FND). In a substantial proportion, PNES are disabling with poor long-term outcomes and high economic costs. Despite the clinical and financial consequences of PNES, there is still a lack of controlled clinical trials on the treatment of this challenging disorder. The study aims to evaluate the feasibility and collect first evidence of the efficacy of a group based-intervention in PNES-patients.!##!Methods!#!A pilot randomized controlled feasibility study with a parallel-group design was performed in adult outpatients with PNES to evaluate a new body-focused group therapy (CORDIS) versus guided self-help groups. Self-assessment of dissociation (Dissociation Experience Scale-DES-20) and seizure severity (Liverpool Seizure Severity Scale-LSSS) were assessed two weeks before and two weeks after the treatment intervention and also six months after treatment as primary outcome parameters.!##!Results!#!A total of 53 patients were recruited from a specialized outpatient clinic, and out of those, 29 patients completed either the body-focused group therapy program (n = 15) or a guided self-help group (SHG) therapy (n = 14). When analyzing the ITT sample (n = 22 CORDIS group, n = 20 SHG), both groups showed an effect on seizure severity and level of dissociation. In the per protocol sample (n = 13 CORDIS group, n = 12 SHG), CORDIS was superior to the self-help group for reducing seizure severity 6 months after the treatment.!##!Significance!#!CORDIS is a newly developed body-focused group therapy program for adults with PNES. Further studies should include a multicentric design with a higher number of participants. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://repository.publisso.de/resource/frl:6450230Test; https://doi.org/10.1007/s00415-021-10652-0Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739289Test/ |
| DOI: | 10.1007/s00415-021-10652-0 |
| الإتاحة: | https://doi.org/10.1007/s00415-021-10652-0Test https://repository.publisso.de/resource/frl:6450230Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739289Test/ |
| حقوق: | https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.5B88ED3C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00415-021-10652-0 |
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