دورية أكاديمية
Effects of acute endurance exercise on plasma protein profiles of endurance-trained and untrained individuals over time
| العنوان: | Effects of acute endurance exercise on plasma protein profiles of endurance-trained and untrained individuals over time |
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| المؤلفون: | Schild, Marius, Eichner, Gerrit, Beiter, Thomas, Zügel, Martina, Krumholz-Wagner, Ilke, Hudemann, Jens, Pilat, Christian, Krüger, Karsten, Niess, Andreas M., Steinacker, Jürgen M., Mooren, Frank C. |
| سنة النشر: | 2022 |
| المجموعة: | Publication Server of the Justus-Liebig-University of Giessen |
| مصطلحات موضوعية: | ddc:610 |
| الوصف: | Acute physical exercise and repeated exercise stimuli affect whole-body metabolic and immunologic homeostasis. The aim of this study was to determine plasma protein profiles of trained (EET, n=19) and untrained (SED, n=17) individuals at rest and in response to an acute bout of endurance exercise. Participants completed a bicycle exercise test at an intensity corresponding to 80% of their VO2max. Plasma samples were taken before, directly after, and three hours after exercise and analyzed using multiplex immunoassays. Seventy-eight plasma variables were included in the final analysis. Twenty-nine variables displayed significant acute exercise effects in both groups. Seven proteins differed between groups, without being affected by acute exercise. Among these A2Macro and IL-5 were higher in EET individuals while leptin showed elevated levels in SED individuals. Fifteen variables revealed group and time differences with elevated levels for IL-3, IL-7, IL-10, and TNFR2 in EET individuals. An interaction effect could be observed for nine variables including IL-6, MMP-2, MMP-3, and muscle damage markers. The proteins that differ between groups indicate a long-term exercise effect on plasma protein concentrations. These findings might be of importance in the development of exercise-based strategies in the prevention and therapy of chronic metabolic and inflammatory diseases and for training monitoring. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://nbn-resolving.de/urn:nbn:de:hebis:26-opus-123161Test; https://jlupub.ub.uni-giessen.de//handle/jlupub/9220Test; http://dx.doi.org/10.22029/jlupub-8608Test |
| DOI: | 10.22029/jlupub-8608 |
| الإتاحة: | https://doi.org/10.22029/jlupub-8608Test http://nbn-resolving.de/urn:nbn:de:hebis:26-opus-123161Test https://jlupub.ub.uni-giessen.de//handle/jlupub/9220Test |
| حقوق: | Namensnennung 3.0 International ; https://creativecommons.org/licenses/by/3.0Test/ |
| رقم الانضمام: | edsbas.1E452ACE |
| قاعدة البيانات: | BASE |
| DOI: | 10.22029/jlupub-8608 |
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