دورية أكاديمية
New anthraquinone derivatives from the stem barks of Morinda lucida Benth
العنوان: | New anthraquinone derivatives from the stem barks of Morinda lucida Benth |
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المؤلفون: | Ekon, Jean Pierre Longue, Zra, Tize, Songue, Jules Lobe, Ngoko, Mireille Laura Wondja, Ngassoum, Martin Benoit, Talla, Emmanuel, Waffo, Alain Francois Kamdem, Sewald, Norbert, Wansi, Jean Duplex |
بيانات النشر: | Elsevier |
سنة النشر: | 2020 |
المجموعة: | PUB - Publications at Bielefeld University |
مصطلحات موضوعية: | Rubiaceae, Morinda lucida, Anthraquinone, Antimicrobial activities |
الوصف: | Ekon JPL, Zra T, Songue JL, et al. New anthraquinone derivatives from the stem barks of Morinda lucida Benth. Phytochemistry Letters . 2020;39:94-98. ; Three new anthraquinone derivatives including (2S, 3R)-1,2,3,4-tetrahydro-2,3,6-trihydroxy-2-methylan-thracene-9,10-dione (1), 3,6-dihydroxy-1,2-dimethoxyanthraquinone (2) and 1,6-dihydroxy-2-hydroxymethyl5-methoxyanthraquinone (3) together with thirteen known compounds including eleven anthraquinones and two triterpenes were isolated from the methanolic crude extract of the stem barks of Morinda lucida. The structures of the new compounds were unambiguously elucidated on the basis of modern NMR spectroscopic methods, as well as by high-resolution mass spectrometry. The known compounds were identified on the basis of their spectral characteristics and by comparison with literature data. The antimicrobial activities of (2S, 3R)1,2,3,4-tetrahydro-2,3,6-trihydroxy-2-methylanthracene-9,10-dione (1), the methanolic crude extract and its fractions were evaluated against five bacteria and four fungi. The lowest values of the MIC (256 mu g/mL) were recorded on Candida parapsilosis, Cryptococcus neoformans for the methanolic crude extract and on Salmonella typhi for the ethyl acetate fraction. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
العلاقة: | info:eu-repo/semantics/altIdentifier/issn/1874-3900; info:eu-repo/semantics/altIdentifier/issn/1876-7486; info:eu-repo/semantics/altIdentifier/wos/000585754900017; https://pub.uni-bielefeld.de/record/2949709Test |
الإتاحة: | https://doi.org/10.1016/j.phytol.2020.06.010Test https://pub.uni-bielefeld.de/record/2949709Test |
حقوق: | info:eu-repo/semantics/closedAccess |
رقم الانضمام: | edsbas.B4593FB5 |
قاعدة البيانات: | BASE |
الوصف غير متاح. |