دورية أكاديمية
Acute Respiratory Distress Syndrome and Risk of AKI among Critically Ill Patients.
| العنوان: | Acute Respiratory Distress Syndrome and Risk of AKI among Critically Ill Patients. |
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| المؤلفون: | Darmon, Michael, Clec'H, Christophe, Adrie, Christophe, Argaud, Laurent, Allaouchiche, Bernard, Azoulay, Elie, Bouadma, Lila, Garrouste-Orgeas, Maïté, Haouache, Hakim, Schwebel, Carole, Goldgran-Toledano, Dany, Khallel, Hatem, Dumenil, Anne-Sylvie, Jamali, Samir, Souweine, Bertrand, Zeni, Fabrice, Cohen, Yves, Timsit, Jean-François |
| المساهمون: | Centre Hospitalier Universitaire de Saint-Etienne (CHU de Saint-Etienne), Institut d'oncologie/développement Albert Bonniot de Grenoble (INSERM U823), Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-EFS-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Cochin AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hospices Civils de Lyon (HCL), Hopital Saint-Louis AP-HP (AP-HP), Université Paris Diderot - Paris 7 (UPD7), Groupe Hospitalier Paris Saint Joseph, Hôpital Delafontaine, Centre Hospitalier de Saint-Denis Ile-de-France, Centre Hospitalier Universitaire Grenoble (CHU), Clinique de réanimation médicale, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-Hôpital Michallon, Groupe Hospitalier Intercommunal Le Raincy-Montfermeil, Centre Hospitalier Andrée Rosemon Cayenne, Guyane Française, CHU Saint-Antoine AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital de Dourdan, CHU Gabriel Montpied Clermont-Ferrand, CHU Clermont-Ferrand, Laboratoire Microorganismes : Génome et Environnement (LMGE), Université Clermont Auvergne 2017-2020 (UCA 2017-2020 )-Centre National de la Recherche Scientifique (CNRS), Université Jean Monnet - Saint-Étienne (UJM), Service d'anesthésie-réanimation Avicenne, Université Paris 13 (UP13)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Avicenne AP-HP |
| المصدر: | ISSN: 1555-9041. |
| بيانات النشر: | HAL CCSD American Society of Nephrology |
| سنة النشر: | 2014 |
| المجموعة: | Portail HAL de l'Université Lumière Lyon 2 |
| مصطلحات موضوعية: | [SDV.MP.PRO]Life Sciences [q-bio]/Microbiology and Parasitology/Protistology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.IB]Life Sciences [q-bio]/Bioengineering |
| الوصف: | International audience ; BACKGROUND AND OBJECTIVES: Increasing experimental evidence suggests that acute respiratory distress syndrome (ARDS) may promote AKI. The primary objective of this study was to assess ARDS as a risk factor for AKI in critically ill patients.DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This was an observational study on a prospective database fed by 18 intensive care units (ICUs). Patients with ICU stays >24 hours were enrolled over a 14-year period. ARDS was defined using the Berlin criteria and AKI was defined using the Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease criteria. Patients with AKI before ARDS onset were excluded.RESULTS: This study enrolled 8029 patients, including 1879 patients with ARDS. AKI occurred in 31.3% of patients and was more common in patients with ARDS (44.3% versus 27.4% in patients without ARDS; P<0.001). After adjustment for confounders, both mechanical ventilation without ARDS (odds ratio [OR], 4.34; 95% confidence interval [95% CI], 3.71 to 5.10) and ARDS (OR, 11.01; 95% CI, 6.83 to 17.73) were independently associated with AKI. Hospital mortality was 14.2% (n=1140) and was higher in patients with ARDS (27.9% versus 10.0% in patients without ARDS; P<0.001) and in patients with AKI (27.6% versus 8.1% in those without AKI; P<0.001). AKI was associated with higher mortality in patients with ARDS (42.3% versus 20.2%; P<0.001).CONCLUSIONS: ARDS was independently associated with AKI. This study suggests that ARDS should be considered as a risk factor for AKI in critically ill patients. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/24875195; hal-01053792; https://hal.science/hal-01053792Test; PUBMED: 24875195; PUBMEDCENTRAL: PMC4123396 |
| DOI: | 10.2215/CJN.08300813 |
| الإتاحة: | https://doi.org/10.2215/CJN.08300813Test https://hal.science/hal-01053792Test |
| رقم الانضمام: | edsbas.24AF3F09 |
| قاعدة البيانات: | BASE |
| DOI: | 10.2215/CJN.08300813 |
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