دورية أكاديمية
Pre-exposure prophylaxis of HIV: A right way to go or a long way to go?
| العنوان: | Pre-exposure prophylaxis of HIV: A right way to go or a long way to go? |
|---|---|
| المؤلفون: | Yu, Wenya, Wang, Lu, Han, Na, Zhang, Xiayan, Mahapatra, Tanmay, Mahapatra, Sanchita, Babu, Giridhar R., Tang, Weiming, Detels, Roger, Zhao, Jinkou |
| المساهمون: | Tang, WM (reprint author), Univ N Carolina, Project China, Guangzhou, Guangdong, Peoples R China., Shijiazhuang Ctr Dis Control & Prevent, Shijia Zhuang, Peoples R China., Chinese Ctr Dis Control & Prevent, Natl Ctr AIDS STD Control & Prevent, Beijing, Peoples R China., Peking Univ Peoples Hosp, Inst Clin Mol Biol, Beijing, Peoples R China., Mission Arogya Hlth & Informat Technol Res Fdn, Kolkata, India., Publ Hlth Fdn India, Indian Inst Publ Hlth, Bengaluru, India., Univ N Carolina, Project China, Guangzhou, Guangdong, Peoples R China., Univ Calif Los Angeles, Fielding Sch Publ Hlth, Dept Epidemiol, Los Angeles, CA USA., Global Fund Fight AIDS TB & Malaria, Impact Results & Evaluat Dept, Geneva, Switzerland. |
| المصدر: | EI ; PubMed ; SCI |
| بيانات النشر: | ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY |
| سنة النشر: | 2016 |
| المجموعة: | Peking University Institutional Repository (PKU IR) / 北京大学机构知识库 |
| مصطلحات موضوعية: | antiretroviral therapy, controlling the HIV epidemic, HIV prevention, pre-exposure prophylaxis, prevention of HIV spread, SEXUAL RISK BEHAVIOR, ACTIVE ANTIRETROVIRAL THERAPY, HUMAN-IMMUNODEFICIENCY-VIRUS, RESOURCE-LIMITED SETTINGS, CONTROLLED PHASE-3 TRIAL, HOMOSEXUAL-MEN, MALE CIRCUMCISION, DRUG-RESISTANCE, PUBLIC-HEALTH, DOUBLE-BLIND |
| الوصف: | Antiretroviral drugs are being tried as candidates for the pre-exposure prophylaxis (PrEP) against HIV for a considerable period, due to their potential for immediate inhibition of viral replication. Discrepancies in the findings called for a critical review of the relevant efforts and their outcomes. A systematic literature search identified 143 eligible articles of which only 5 reported complete findings while another 11 were still on-going. Observed moderate efficacy and good safety profile seemed to identify PrEP as a promising step for minimizing the spread of HIV to relatively unaffected population and controlling the epidemic among high risk population groups. But the duration of this efficacy was found to depend heavily on the availability, adherence and other related issues like cost, political commitment, ethical consideration etc. To prevent potential cultural and behavioral modifications, proper pre-administration counseling also seemed critical for the success of PrEP as a cost-effective intervention with adequate coverage. ; FIC NIH HHS [D43 TW009532]; NCATS NIH HHS [UL1 TR000124]; NIAID NIH HHS [P30 AI028697]; NIMH NIH HHS [P30 MH058107] ; SCI(E) ; EI ; PubMed ; ARTICLE ; drtanmaymahapatra@yahoo.com; 2985786008@qq.com ; 1 ; 201-208 ; 44 |
| نوع الوثيقة: | journal/newspaper |
| اللغة: | English |
| تدمد: | 2169-1401 2169-141X |
| العلاقة: | ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY.2016,44,(1),201-208.; 1393216; http://hdl.handle.net/20.500.11897/436146Test; WOS:000368022400027 |
| DOI: | 10.3109/21691401.2014.934458 |
| الإتاحة: | https://doi.org/20.500.11897/436146Test https://doi.org/10.3109/21691401.2014.934458Test https://hdl.handle.net/20.500.11897/436146Test |
| رقم الانضمام: | edsbas.2776FE1 |
| قاعدة البيانات: | BASE |
| تدمد: | 21691401 2169141X |
|---|---|
| DOI: | 10.3109/21691401.2014.934458 |