دورية أكاديمية
American Society of Blood and Marrow Transplantation, European Society of Blood and Marrow Transplantation, Blood and Marrow Transplant Clinical Trials Network, and International Myeloma Working Group Consensus Conference on Salvage Hematopoietic
| العنوان: | American Society of Blood and Marrow Transplantation, European Society of Blood and Marrow Transplantation, Blood and Marrow Transplant Clinical Trials Network, and International Myeloma Working Group Consensus Conference on Salvage Hematopoietic |
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| المؤلفون: | Giralt, Sergio, Garderet, Laurent, Durie, Brian, Cook, Gordon, Gahrton, Gosta, Bruno, Benedetto, Hari, Paremesweran, Lokhorst, Henk, McCarthy, Phillip, Krishnan, Amrita, Sonneveld, Pieter, Goldschmidt, Harmut, Jagannath, Sundar, Barlogie, Bart, Mateos, Maria, Gimsing, Peter, Sezer, Orhan, Mikhael, Joseph, Lu, Jin, Dimopoulos, Meletios, Mazumder, Amitabha, Palumbo, Antonio, Abonour, Rafat, Anderson, Kenneth, Attal, Michel, Blade, Joan, Bird, Jenny, Cavo, Michele, Comenzo, Raymond, de la Rubia, Javier, Einsele, Hermann, Garcia-Sanz, Ramon |
| المساهمون: | Giralt, S (reprint author), Mem Sloan Kettering Canc Ctr, 1275 York Ave,Box 235, New York, NY 10065 USA., Mem Sloan Kettering Canc Ctr, Weill Cornell Med Coll, New York, NY 10065 USA., Hop St Antoine, INSERM, UMRS 938, F-75571 Paris, France., Int Myeloma Fdn, Los Angeles, CA USA., St James Univ Hosp, Leeds LS9 7TF, W Yorkshire, England., Karolinska Inst, Huddinge, Sweden., Univ Turin, Turin, Italy., Med Coll Wisconsin, Milwaukee, WI 53226 USA., Univ Med Ctr Utrecht, Utrecht, Netherlands., Roswell Pk Canc Inst, Buffalo, NY 14263 USA., City Hope Canc Ctr Duarte, Duarte, CA USA., Erasmus MC, Rotterdam, Netherlands., Heidelberg Univ, Heidelberg, Germany., Mt Sinai Sch Med, New York, NY USA., Hosp Univ Salamanca, Salamanca, Spain., Rigshosp, DK-2100 Copenhagen, Denmark., Mem Sisli Hastanesi, Istanbul, Turkey., Mayo Clin, Scottsdale, AZ USA., Peking Univ, Inst Hematol, Peoples Hosp, Beijing 100871, Peoples R China., Univ Athens, Alexandra Hosp, Athens 11528, Greece., NYU, Sch Med, New York, NY USA., Indiana Univ, Melvin & Bren Simon Canc Ctr, Indianapolis, IN 46204 USA., Harvard Univ, Dana Farber Canc Inst, Boston, MA 02115 USA., Inst Claudius Regaud, Toulouse, France., IDIBAPS, Hosp Clin, Barcelona, Spain., Univ Hosp Bristol, Bristol, Avon, England., Univ Bologna, Sch Med, Seragnoli Inst Hematol, Bologna, Italy., Tufts Univ, Sch Med, Boston, MA 02111 USA., Hosp Dr Pesset, Valencia, Spain., Klin Univ Wurzburg, Wurzburg, Germany., Aalborg Univ Hosp, Aalborg, Denmark., Univ Sydney, Sch Med, Royal Prince Alfred Hosp, Sydney, NSW 2006, Australia., Mayo Clin Rochester, Rochester, MN USA., Hosp Claude Huriez, Lille, France., Emory Univ, Sch Med, Winship Canc Inst, Atlanta, GA USA., Wilhelminenkrebsforsch Inst, Vienna, Austria., Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA., Dalhousie Univ, Sch Med, Dalhousie, NS, Canada., Hosp Clin Montevideo, Montevideo, Uruguay., Univ Navarra Clin, Navarra, Spain., Skane Univ Hosp, Malmo, Sweden., Levine Canc Inst, Charlotte, NC USA., John Theurer Canc Ctr, Hackensack, NJ USA., Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA., Ohio State Univ, Med Ctr, Columbus, OH 43210 USA., Univ Paris 06, Hosp St Antoine, Paris, France., Duke Univ Hosp, Durham, NC USA., Oregon Hlth & Sci Univ, Portland, OR USA., Sarah Cannon Res Inst, Nashville, TN USA., Ottawa Hosp Res Inst, Ottawa, ON, Canada., Univ Hosp Nantes, Nantes, France., Univ Hamburg Hosp, Hamburg, Germany., Univ Penn, Abramson Canc Ctr, Philadelphia, PA 19104 USA., Mem Sloan Kettering Canc Ctr, 1275 York Ave,Box 235, New York, NY 10065 USA. |
| المصدر: | SCI ; PubMed |
| بيانات النشر: | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION |
| سنة النشر: | 2015 |
| المجموعة: | Peking University Institutional Repository (PKU IR) / 北京大学机构知识库 |
| مصطلحات موضوعية: | Myeloma, Stem cell transplantation, Salvage therapy, LENALIDOMIDE PLUS DEXAMETHASONE, BORTEZOMIB-THALIDOMIDE-DEXAMETHASONE, LOW-DOSE DEXAMETHASONE, RANDOMIZED PHASE-III, AUTOLOGOUS TRANSPLANTATION, ALLOGENEIC TRANSPLANTATION, COMBINATION THERAPY, FOLLOW-UP, MAINTENANCE, PROGRESSION |
| الوصف: | In contrast to the upfront setting in which the role of high-dose therapy with autologous hematopoietic cell transplantation (HCT) as consolidation of a first remission in patients with multiple myeloma (MM) is well established, the role of high-dose therapy with autologous or allogeneic HCT has not been extensively studied in MM patients relapsing after primary therapy. The International Myeloma Working Group together with the Blood and Marrow Transplant Clinical Trials Network, the American Society of Blood and Marrow Transplantation, and the European Society of Blood and Marrow Transplantation convened a meeting of MM experts to: (1) summarize current knowledge regarding the role of autologous or allogeneic HCT in MM patients progressing after primary therapy, (2) propose guidelines for the use of salvage HCT in MM, (3) identify knowledge gaps, (4) propose a research agenda, and (5) develop a collaborative initiative to move the research agenda forward. After reviewing the available data, the expert committee came to the following consensus statement for salvage autologous HCT: (1) In transplantation-eligible patients relapsing after primary therapy that did NOT include an autologous HCT, high-dose therapy with HCT as part of salvage therapy should be considered standard; (2) High-dose therapy and autologous HCT should be considered appropriate therapy for any patients relapsing after primary therapy that includes an autologous HCT with initial remission duration of more than 18 months; (3) High-dose therapy and autologous HCT can be used as a bridging strategy to allogeneic HCT; (4) The role of postsalvage HCT maintenance needs to be explored in the context of well-designed prospective trials that should include new agents, such as monoclonal antibodies, immune-modulating agents, and oral proteasome inhibitors; (5) Autologous Ha consolidation should be explored as a strategy to develop novel conditioning regimens or post-HCT strategies in patients with short (less than 18 months remissions) after primary ... |
| نوع الوثيقة: | journal/newspaper |
| اللغة: | Chinese |
| تدمد: | 1083-8791 1523-6536 |
| العلاقة: | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION.2015,21,(12),2039-2051.; 1296370; http://hdl.handle.net/20.500.11897/417766Test; WOS:000364981700003 |
| DOI: | 10.1016/j.bbmt.2015.09.016 |
| الإتاحة: | https://doi.org/20.500.11897/417766Test https://doi.org/10.1016/j.bbmt.2015.09.016Test https://hdl.handle.net/20.500.11897/417766Test |
| رقم الانضمام: | edsbas.F6B045D4 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 10838791 15236536 |
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| DOI: | 10.1016/j.bbmt.2015.09.016 |